PMC:7289100 / 7260-9354 JSONTXT 12 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T38 0-187 Sentence denotes GBS is a progressive, ascending, symmetrical flaccid limbs paralysis, along with areflexia or hyporeflexia with or without cranial nerve involvement which can progress over days to weeks.
T39 188-273 Sentence denotes The disease may be triggered by respiratory or intestinal infections or vaccinations.
T40 274-456 Sentence denotes The known triggering infections include Influenza; Chlamydia; CMV; varicella; mumps; rubella; HIV; Polio; Hepatitis E; Borrelia; Mycoplasma pneumonia as well as Campilobacter Jejuni.
T41 457-657 Sentence denotes GBS is an immune-mediated disorder with molecular mimicry playing an important role in its autoimmune disorder in which the immune system attacks gangliosides on the peripheral nervous system [34,35].
T42 658-735 Sentence denotes There are so far 2 reports of GBS associated with Covid-19 infection [36,37].
T43 736-844 Sentence denotes It is yet unclear whether Covid-19 induces the production of antibodies against these specific gangliosides.
T44 845-980 Sentence denotes The first is a report of five out of 1200 patients hospitalized between February 28th and March 21st, 2020 in Northern Italy hospitals.
T45 981-1071 Sentence denotes The onset of neurological symptoms began 7–10 days after the initial respiratory symptoms.
T46 1072-1207 Sentence denotes Four out of the 5 patients had lower-limb weakness and paresthesia and one was with facial diplegia followed by ataxia and paresthesia.
T47 1208-1318 Sentence denotes Generalized, flaccid tetraparesis or tetraplegia evolved over a period of 36 h to 4 days in 4 of the patients.
T48 1319-1365 Sentence denotes Three of them required mechanical ventilation.
T49 1366-1427 Sentence denotes Anti-ganglioside antibodies were either negative or not done.
T50 1428-1521 Sentence denotes All patients received IVIG (1 of then required 2 cycles) and one had started plasma exchange.
T51 1522-1726 Sentence denotes The second report from Iran describes a 65 year old male patient admitted to hospital because of acute progressive symmetric ascending quadriparesis, two weeks after a history of cough, fever and dyspnea.
T52 1727-1760 Sentence denotes Covid-19 was diagnosed by RT-PCR.
T53 1761-1846 Sentence denotes The patient was treated by hydroxychloroquine, Lopinavir/Ritonavir, and Azithromycin.
T54 1847-1872 Sentence denotes GBS was confirmed by EMG.
T55 1873-1916 Sentence denotes The patient was treated by IVIG for 5 days.
T56 1917-2094 Sentence denotes Another early report of a single GBS patient came from China during the SARS-CoV-2 epidemic, although there is some concern regarding the causality in this particular case [38].