Id |
Subject |
Object |
Predicate |
Lexical cue |
T38 |
0-187 |
Sentence |
denotes |
GBS is a progressive, ascending, symmetrical flaccid limbs paralysis, along with areflexia or hyporeflexia with or without cranial nerve involvement which can progress over days to weeks. |
T39 |
188-273 |
Sentence |
denotes |
The disease may be triggered by respiratory or intestinal infections or vaccinations. |
T40 |
274-456 |
Sentence |
denotes |
The known triggering infections include Influenza; Chlamydia; CMV; varicella; mumps; rubella; HIV; Polio; Hepatitis E; Borrelia; Mycoplasma pneumonia as well as Campilobacter Jejuni. |
T41 |
457-657 |
Sentence |
denotes |
GBS is an immune-mediated disorder with molecular mimicry playing an important role in its autoimmune disorder in which the immune system attacks gangliosides on the peripheral nervous system [34,35]. |
T42 |
658-735 |
Sentence |
denotes |
There are so far 2 reports of GBS associated with Covid-19 infection [36,37]. |
T43 |
736-844 |
Sentence |
denotes |
It is yet unclear whether Covid-19 induces the production of antibodies against these specific gangliosides. |
T44 |
845-980 |
Sentence |
denotes |
The first is a report of five out of 1200 patients hospitalized between February 28th and March 21st, 2020 in Northern Italy hospitals. |
T45 |
981-1071 |
Sentence |
denotes |
The onset of neurological symptoms began 7–10 days after the initial respiratory symptoms. |
T46 |
1072-1207 |
Sentence |
denotes |
Four out of the 5 patients had lower-limb weakness and paresthesia and one was with facial diplegia followed by ataxia and paresthesia. |
T47 |
1208-1318 |
Sentence |
denotes |
Generalized, flaccid tetraparesis or tetraplegia evolved over a period of 36 h to 4 days in 4 of the patients. |
T48 |
1319-1365 |
Sentence |
denotes |
Three of them required mechanical ventilation. |
T49 |
1366-1427 |
Sentence |
denotes |
Anti-ganglioside antibodies were either negative or not done. |
T50 |
1428-1521 |
Sentence |
denotes |
All patients received IVIG (1 of then required 2 cycles) and one had started plasma exchange. |
T51 |
1522-1726 |
Sentence |
denotes |
The second report from Iran describes a 65 year old male patient admitted to hospital because of acute progressive symmetric ascending quadriparesis, two weeks after a history of cough, fever and dyspnea. |
T52 |
1727-1760 |
Sentence |
denotes |
Covid-19 was diagnosed by RT-PCR. |
T53 |
1761-1846 |
Sentence |
denotes |
The patient was treated by hydroxychloroquine, Lopinavir/Ritonavir, and Azithromycin. |
T54 |
1847-1872 |
Sentence |
denotes |
GBS was confirmed by EMG. |
T55 |
1873-1916 |
Sentence |
denotes |
The patient was treated by IVIG for 5 days. |
T56 |
1917-2094 |
Sentence |
denotes |
Another early report of a single GBS patient came from China during the SARS-CoV-2 epidemic, although there is some concern regarding the causality in this particular case [38]. |