PMC:7289100 / 47965-49286 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T316 0-145 Sentence denotes Based upon the possibility to detect autoimmune reactions by morphological methods we analyzed autopsies from 18 deceased patients from COVID-19.
T317 146-268 Sentence denotes The pathological investigation was done by using bright lineage of immunohistochemistry (CD2, 3, 5, 7, 8, 20, 31, 34, 69).
T318 269-353 Sentence denotes Our study allowed us to demonstrate the role of different mechanisms of death [128].
T319 354-580 Sentence denotes Of special interest was the diffuse infiltration of the lungs, along with focal infiltration of the kidney, liver, intestine, adrenals, pancreas and pericard by lymphocytes, which were seen in different grade in all our cases.
T320 581-893 Sentence denotes In order to understand its nature we were able to prove that the infiltrate was dominated by T lymphocytes (CD3+), and the most numerous of them were CD8+ suppressors, observed in the lungs (Fig. 1a), adrenals (Fig. 1b), liver (Fig. 1c), intestine (Fig. 1d) and other organs partly accompanied by tissue lesions.
T321 894-1084 Sentence denotes Taking in to consideration that one of the most important mechanisms of autoimmune reactions is CD8+ T Cell mediated cytotoxicity, we assumed that the findings confirm an autoimmune process.
T322 1085-1179 Sentence denotes Further complex studies will hopefully allow us to optimize the strategy of treatment as well.
T323 1180-1247 Sentence denotes Fig. 1 Infiltration by CD8+ suppressor T-cells of different organs.
T324 1248-1252 Sentence denotes IHC.
T325 1253-1271 Sentence denotes Magnification 100.
T326 1272-1321 Sentence denotes A-Lungs, B -Adrenal gland, C-liver, D- intestine.