LitCovid-sentences  

PMC:7289100 / 17694-19546 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T114 0-99 Sentence denotes Kawasaki disease (KD) is a systemic vasculitis that usually affects children less than 5 years old.
T115 100-296 Sentence denotes Soon after the first description by Tomisaku Kawasaki in 1967, it was clear that the disease, although self-limiting, might cause coronary artery aneurism (CAA) in a high percentage of cases [61].
T116 297-410 Sentence denotes KD is nowadays considered as the first cause of acquired heart disease in children from developed countries [62].
T117 411-526 Sentence denotes The disease is far more common in eastern countries, and in children of eastern origin living in western countries.
T118 527-663 Sentence denotes For example, the 2010 annual incidence for KD was 222.9 cases/100000 children <5 y/o in Japan, compared to 20/100000 in the USA [63,64].
T119 664-808 Sentence denotes Since no specific test is available, diagnosis relies on the recognition of the cardinal clinical features and the exclusion of other mimickers.
T120 809-1014 Sentence denotes The mainstay of treatment is the administration of intravenous immunoglobulins (IVIG) at 2 g/kg of body weight, as soon as the diagnosis is established, and possibly within 10 days from the onset of fever.
T121 1015-1074 Sentence denotes IVIG have been demonstrated to reduce the risk of CAA [65].
T122 1075-1262 Sentence denotes A subgroup of patients, accounting for nearly 5% of those with KD, has been described to have a very severe disease onset with systolic hypotension or shock (Kawasaki Shock Syndrome-KSS).
T123 1263-1369 Sentence denotes The shock may be caused by a capillary leak syndrome or by poor perfusion due to inflammatory myocarditis.
T124 1370-1673 Sentence denotes KSS patients are more likely to be females and to have earlier onset, incomplete presentations, and more severe laboratory abnormalities (lower platelet counts, higher serum CRP levels, hyponatremia, increased transaminases, metabolic acidosis, consumptive coagulopathy, and lower serum albumin levels).
T125 1674-1852 Sentence denotes Patients with KSS are often resistant to IVIG treatment and have a higher incidence of coronary artery aneurysms, mitral regurgitation, and prolonged myocardial dysfunction [66].