LitCovid-sentences  

PMC:7283670 / 128174-132418 JSONTXT 10 Projects

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Id Subject Object Predicate Lexical cue
T1057 0-34 Sentence denotes 7.5 Other future possible options
T1058 36-69 Sentence denotes 7.5.1 Convalescent blood therapy
T1059 70-236 Sentence denotes A conspicuously conventional method, transfusion of human convalescent plasma, might be viewed as a beneficial strategy for prevention and even treatment of COVID‐19.
T1060 237-400 Sentence denotes The method is as facile as its age since it only requires an adequate number of recovered patients who are willing to donate their immunoglobulin‐containing serum.
T1061 401-602 Sentence denotes Although one still might argue the possibility of SARS‐CoV‐2 infection via convalescent blood transfusion, no such incident with SARS‐CoV was reported by WHO amidst the outbreak of the disease in 2003.
T1062 603-938 Sentence denotes The heft of past experience should come to mind once it is noted that the majority of approaches and therapeutic strategies that are currently being tested for COVID‐19 are derived from clinical experience in treatment of SARS, MERS, and other correspondents viral epidemics (Casadevall & Pirofski, 2020; Cunningham, Goh, & Koh, 2020).
T1063 940-982 Sentence denotes 7.5.2 Mesenchymal stem cell (MSC) therapy
T1064 983-1142 Sentence denotes A new therapeutic for treating immune‐mediated diseases, MSC therapy might have the capability to terminate the inappropriate release of cytokines in COVID‐19.
T1065 1143-1284 Sentence denotes Through its anti‐inflammatory effects, MSC therapy has been reported to improve respiratory function in murine models with acute lung injury.
T1066 1285-1459 Sentence denotes Evidence suggests that MSCs might be doing so by repressing the aberrant release of inflammatory factors (Hu & Li, 2018; Wang, Yao, Lv, Ling, & Li, 2017; Xiang et al., 2017).
T1067 1460-1698 Sentence denotes In particular, a study by Chinese scientists concluded that transplantation of MSCs could be considered as a novel approach in treatment of viral pneumonia, noting promissory implications of this method in management of H7N9‐induced ARDS.
T1068 1699-1919 Sentence denotes Since H7N9 and SARS‐CoV‐2 can result in similar complications, for example, ARDS and respiratory failure, MSC‐based therapy might lead to a new path in treatment of COVID‐19‐associated pneumonia (Chen, Hu, et al., 2020).
T1069 1921-1954 Sentence denotes 7.5.3 Nano drug delivery systems
T1070 1955-2194 Sentence denotes It has long been known that the traditional circulation‐based delivery of therapeutic agents is not as effect, prompting pharmaceutical industries to develop novel platforms for delivery of molecules to hard‐to‐reach tissues in human body.
T1071 2195-2453 Sentence denotes Conjugation of antiviral agents, particularly nucleoside analogs, with specific nanoparticles has proved to be effectual in treatment of resistant HIV infection (Agarwal, Chhikara, Doncel, & Parang, 2017; Agarwal, Chhikara, Quiterio, Doncel, & Parang, 2012).
T1072 2454-2741 Sentence denotes Today, an appreciable number of drug delivery platforms based on nanotechnology are available that can be experimentally used with custom therapeutic formulations for treatment of COVID‐19 (Chhikara & Varma, 2019) in hopes of shortening the course of the disease (Chhikara et al., 2020).
T1073 2743-2777 Sentence denotes 7.5.4 Psychological interventions
T1074 2778-2949 Sentence denotes Progression of COVID‐19, similar to any other disease, can result in suffering of the patients, prompting psychological symptoms, which will require special interventions.
T1075 2950-3125 Sentence denotes It has been well‐established today that individuals who fall victim to public health emergencies, for example, disease outbreaks, develop variable degrees of stress disorders.
T1076 3126-3292 Sentence denotes The problem persists even after the individual has recovered and discharged from the hospital (Cheng, Wong, Tsang, & Wong, 2004; Fan, Long, Zhou, Zheng, & Liu, 2015).
T1077 3293-3583 Sentence denotes With that in mind, one should consider several factors for classification of patients who will most probably benefit from psychological interventions; that is overall course of the disease, severity, and quality of hospitalization (e.g., home, ordinary wards, ICU, etc.) (Duan & Zhu, 2020).
T1078 3584-3753 Sentence denotes In large‐scale outbreaks such as COVID‐19 epidemic, healthcare workers become the frontline at providing psychological cares for patients who battle against the disease.
T1079 3754-3915 Sentence denotes Primary medical and mental care should be provided for those individuals who are recognized as “suspected case” and duly quarantined at home. (Duan & Zhu, 2020).
T1080 3916-4244 Sentence denotes Interventions should be discreetly formulated following a thorough evaluation of risk factors involved in emerging of these psychological issues, including a history of impaired mental health, bereavement after a deceased family member, panic, separation from loved ones, and a low income (Kun, Han, Chen, Yao, & Anxiety, 2009).