| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1039 |
0-214 |
Sentence |
denotes |
ACE2 is a prominent regulatory arm in the RAAS axis, thus, a disruption in ACE‐Angiotensin II‐Angiotensin Type 1 Receptor (AT1R), and ACE2/Angiotensin‐(1‐7)/Mas Receptor axes can result in multisystem inflammation. |
| T1040 |
215-327 |
Sentence |
denotes |
Increased levels of ACE and Angiotensin II in plasma are considered poor prognostic factors in severe pneumonia. |
| T1041 |
328-473 |
Sentence |
denotes |
Several studies on animal models have reported effectiveness of RAAS inhibitors in alleviation of severe pneumonia and acute respiratory failure. |
| T1042 |
474-627 |
Sentence |
denotes |
In the aftermath of SARS‐CoV‐2 and ACE2 binding, the enzyme is eventually degraded, hence, the inhibition of ACE2/Angiotensin‐(1‐7)/Mas Receptor pathway. |
| T1043 |
628-822 |
Sentence |
denotes |
Accordingly, it is assumed that ACE and AT1R inhibitors might be game‐changing agents that can especially be administered for COVID‐19 patients who have serious impairments in their homeostasis. |
| T1044 |
823-977 |
Sentence |
denotes |
Maintenance of homeostasis may ultimately result in suppression of the inflammatory response, mostly in the pulmonary tissue (Sun, Yang, Sun, & Su, 2020). |
