LitCovid-sentences  

PMC:7283670 / 123601-125251 JSONTXT 9 Projects

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Id Subject Object Predicate Lexical cue
T1028 0-49 Sentence denotes 7.2 Lopinavir/ritonavir, leronlimab, galidesivir
T1029 50-204 Sentence denotes Lopinavir/Ritonavir, commonly used for treatment of HIV infection, has been indicated for treatment of COVID‐19 in a number of reports (Kim et al., 2020).
T1030 205-416 Sentence denotes Previous studies suggested that when combined together, Lopinavir and Ritonavir act in concert to hinder further replication of SARS‐CoV, and improve the clinical status of patients with SARS (Chu et al., 2004).
T1031 417-528 Sentence denotes This might also mean that the well‐known antiretroviral duo can also prove beneficial in treatment of COVID‐19.
T1032 529-761 Sentence denotes Other candidates for possible management of SARS‐CoV‐2 include Leronlimab and Galidesivir, both of which have been of clinical value in treatment of several fatal viral infections, and were shown to improve the survival of patients.
T1033 762-826 Sentence denotes Leronlimab is a humanized monoclonal antibody (CCR5 antagonist).
T1034 827-996 Sentence denotes Galidesivir, on the other hand, belongs to the family of nucleoside RNA polymerase inhibitors (https://www.clinicaltrialsarena.com/analysis/coronavirus-mers-cov-drugs/).
T1035 997-1207 Sentence denotes In the absence of any specific therapeutic agents to quell SARs‐CoV‐2, it might be a salutary strategy to repurpose the already available medicine, and include them in treatment of COVID‐19 (Tian et al., 2020).
T1036 1208-1300 Sentence denotes Several clinical trials can be viewed at ClinicalTrials.gov, that are currently in progress.
T1037 1301-1650 Sentence denotes These trials have specially focused on potency of Remdesivir, immunoglobulins, and combinational therapies, for example, Arbidol hydrochloride with interferon atomization, ASC09F and oseltamivir, ritonavir and oseltamivir, and lopinavir combined with ritonavir (https://clinicaltrials.gov/ct2/results?cond=&2019nCoV&term=&cntry=&state=&city=&dist=).