PMC:7281378 / 76592-83936 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T578 0-4 Sentence denotes 3.6.
T579 5-18 Sentence denotes South America
T580 20-26 Sentence denotes 3.6.1.
T581 27-36 Sentence denotes Argentina
T582 37-211 Sentence denotes After influenza virus outbreak hit a swine farm in Buenos Aires in November 2008, one of the five dead swine were diagnosed with viral pneumonia through immunohistochemistry.
T583 212-380 Sentence denotes A full genome of H3N2 virus sharing 96–98% nucleotide sequence identity with H3N2 viruses reported in North America during 2000–2003 was recovered from the swine [314].
T584 381-598 Sentence denotes An H1N1 virus was reported from a swine after a swine farm manager along with his spouse experienced influenza-like symptoms few days before the outbreak erupted in the swine at a Buenos Aires based farm in June 2009.
T585 599-673 Sentence denotes The influenza disease symptoms lasted for about a week in nursery piglets.
T586 674-843 Sentence denotes Immunohistochemistry identified necrotizing bronchiolitis in four of the swine post-mortem samples while one sample had severe inflammation in the bronchiolar epithelia.
T587 844-1045 Sentence denotes The serological investigation detected IAV antibodies in most of the sera samples collected after 15 days of onset of clinical symptoms however the active infection was reduced to only six swine [315].
T588 1046-1345 Sentence denotes The third investigation carried out histopathology which identified lung lesions compatible to the influenza virus infection in nine swine necropsy samples at a Buenos Aires based swine farm in October 2009 and later in eight swine necropsy samples originated from a Santa Fe based farm in May 2010.
T589 1346-1574 Sentence denotes The swine at Buenos Aires farm were found infected with H1N1 virus while the swine at the Santa Fe farm retrieved one H1N2 and three human-like reassortant A(H1N1)pdm09 virus isolates which had triple reassortant internal genes.
T590 1575-1674 Sentence denotes This was the first report of human-like reassortant A(H1N1)pdm09 virus in swine in Argentina [316].
T591 1675-1914 Sentence denotes Later two more investigations using histopathology, immunohistochemistry, serology, and molecular analyses reported H1N2, H3N2, and reassortant H3N2 viruses with A(H1N1)pdm09 internal genes in swine in Argentina during 2011–2012 [317,318].
T592 1916-1922 Sentence denotes 3.6.2.
T593 1923-1929 Sentence denotes Brazil
T594 1930-2173 Sentence denotes Several H1N1, H1N2, H3N2, human-like H1N1, and A(H1N1)pdm09 viruses have been identified in Brazilian swine from the Minas Gerais, Parana, Rio Grande do Sul and Sao Paulo provinces in Brazil during and after 2009 [319,320,321,322,323,324,325].
T595 2174-2304 Sentence denotes A technician who visited a Minas Gerais swine farm experiencing influenza outbreak developed similar respiratory disease symptoms.
T596 2305-2558 Sentence denotes The nasal swab sample was obtained from the technician, as a result, one A(H1N1)pdm09 virus was isolated which was closely related to the A(H1N1)pdm09 viruses reported from the swine herd in the Minas Gerais which was recently visited by the technician.
T597 2559-2686 Sentence denotes Hence it was concluded that a zoonotic transmission from swine to the technician occurred at the Minas Gerais swine farm [326].
T598 2687-2909 Sentence denotes An immunohistochemical investigation demonstrated microscopic lesions suggesting broncho-interstitial pneumonia in the lung tissues of four severely sick piglets at a swine farm located in Parana province in February 2011.
T599 2910-2966 Sentence denotes The A(H1N1)pdm09 viruses were isolated from two piglets.
T600 2967-3037 Sentence denotes Additionally, a novel reassortant H1N2 virus was also recovered [327].
T601 3038-3139 Sentence denotes One more investigation identified that A(H1N1)pdm09 virus was the most prevalent IAV subtype in sows.
T602 3140-3259 Sentence denotes The co-infections of sows with A(H1N1)pdm09, H1N2, or H3N2 subtypes were also documented in Rio Grande do Sul province.
T603 3260-3406 Sentence denotes These findings were noteworthy because the coinfections may trigger reassortments and thus may facilitate emergence of novel strains of IAV [328].
T604 3407-3520 Sentence denotes Later two more H1N2 viruses were isolated and characterized from swine in Rio Grande do Sul province during 2013.
T605 3521-3725 Sentence denotes The sequences of both the isolates had high nucleotide similarity to each other in different genome segments in the range of 98.9% to 100% which suggested a common source of origin of both isolates [329].
T606 3727-3733 Sentence denotes 3.6.3.
T607 3734-3742 Sentence denotes Colombia
T608 3743-3837 Sentence denotes The A(H1N1)pdm09 virus was identified in seven swine farms in Colombia during 2008–2009 [330].
T609 3839-3845 Sentence denotes 3.6.4.
T610 3846-3850 Sentence denotes Peru
T611 3851-3960 Sentence denotes The A(H1N1)pdm09 virus antibodies were detected in 110 backyard swine in Peru during March 2009–October 2011.
T612 3961-4169 Sentence denotes Total four A(H1N1)pdm09 virus isolates were retrieved and sequenced which determined that there were at least two separate events of A(H1N1)pdm09 virus transmission from human to backyard swine in Peru [331].
T613 4171-4177 Sentence denotes 3.6.5.
T614 4178-4183 Sentence denotes Chile
T615 4184-4282 Sentence denotes The backyard productive systems (BPS) for raising swine, cattle, and poultry are popular in Chile.
T616 4283-4559 Sentence denotes A molecular investigation reported a negative active IAV infection across 113 BPS units within ten counties in Chile during 2012–2014 but the serological investigation detected IAV antibodies in swine at two BPS units which suggested a past exposure of swine to the IAV [332].
T617 4560-4723 Sentence denotes Interestingly, the HA gene sequence of an H12 virus was obtained from a domestic Muscovy duck at one of the BPS which appeared to have originated from a wild bird.
T618 4724-4812 Sentence denotes This suggested a spillover of the IAV from wild reservoir to the domestic poultry [332].
T619 4813-4968 Sentence denotes Another study reported the prevalence of H1N2 virus in swine reared at 40 different BPS having poultry and swine in El Yali wetland during 2013–2014 [333].
T620 4969-5122 Sentence denotes One more study identified four swine sera samples (4/64; 6.3%) that were found positive for IAV antibodies collected from different BPS in Central Chile.
T621 5123-5226 Sentence denotes One pool of swine nasal swab samples (1/39; 2.6%) was also detected IAV positive with real-time RT-PCR.
T622 5227-5362 Sentence denotes Interestingly, 7.9% chicken, 4.3% ducks and 11.1% geese samples collected from 329 BPS in Central Chile also had active IAV infections.
T623 5363-5485 Sentence denotes The breeding practice of poultry and swine in the BPS was determined to be a major risk factor for IAV transmission [334].
T624 5486-5683 Sentence denotes Briefly, the IAV strains of H1N1, H1N2, H3N2, and A(H1N1)pdm09 viruses have been reported from the swine in Argentina and Brazil while A(H1N1)pdm09 virus was reported in swine in Colombia and Peru.
T625 5684-5747 Sentence denotes Swine in Chile were found infected with H1N2 virus (Figure 4F).
T626 5748-5875 Sentence denotes In summary, total 281 research articles were identified which reported several influenza viruses in swine populations globally.
T627 5876-6056 Sentence denotes The highest number of studies were reported from Asia (n = 107), followed by North America (n = 76), Europe (n = 55), South America (n = 21), Africa (n = 18) and Australia (n = 4).
T628 6057-6188 Sentence denotes The highest number of reports per country were documented in United States (n = 40) followed by China (n = 39) and Canada (n = 24).
T629 6189-6275 Sentence denotes Until February 2020, influenza viruses have been reported from 53 countries worldwide.
T630 6276-6411 Sentence denotes Four subtypes of IAV including H1N1, H1N2, H3N2, and A(H1N1)pdm09 viruses were most frequently detected in swine populations (Table 1).
T631 6412-6709 Sentence denotes Most of the large-scale studies used serological investigations including ELISA, hemagglutinin inhibition (HI), neuraminidase inhibition (NI), virus neutralization (VN), or microneutralization (MN) assays for the determination of the seroprevalence and subtyping of the influenza viruses in swine.
T632 6710-6796 Sentence denotes Several investigations used virus isolation for the confirmation and subtyping of IAV.
T633 6797-6944 Sentence denotes Most of the virological investigations used one-step real-time RT-PCR and/or reverse-transcription PCR for influenza virus detection and subtyping.
T634 6945-7143 Sentence denotes Sanger sequencing or next-generation sequencing using MiSeq or Ion Torrent sequencing successfully generated the influenza virus sequences from the swine samples for epidemiological interpretations.
T635 7144-7344 Sentence denotes Histological examinations including immunohistochemistry or immunofluorescence were used to examine the swine lung or other internal organ tissue samples for the influenza virus diagnostics (Table 2).