Id |
Subject |
Object |
Predicate |
Lexical cue |
T42 |
0-183 |
Sentence |
denotes |
Fig. 1 Possible interaction of lysosomotropic agents and lysosome targeting drugs with the replication cycle of severe acute respiratory syndrome corovavirus-2 (SARS-CoV-2) in a cell. |
T43 |
184-374 |
Sentence |
denotes |
Lysosome targeting drugs and lysosomotropic drugs, such as chloroquine, have the ability to interfere with endosomal trafficking, affecting both endosomal maturation and exocytotic pathways. |
T44 |
375-667 |
Sentence |
denotes |
Taking into consideration the dependence of viral replication on the normal functioning of endocytic trafficking, commonly used pharmacological agents that demonstrate lysosomotropic properties should be examined as a possible therapeutic option for the treatment of coronavirus disease 2019. |