LitCovid-sentences  

PMC:7274970 / 6596-13713 JSONTXT 11 Projects

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Id Subject Object Predicate Lexical cue
T40 0-24 Sentence denotes 2 Materials and methods
T41 26-60 Sentence denotes 2.1 Study design and participants
T42 61-325 Sentence denotes For this single-center retrospective study, 449 hospitalized patients with laboratory confirmed COVID-19 admitted to the West District of Wuhan Union Hospital between January 25 and March 15, 2020 were screened using the following inclusion and exclusion criteria.
T43 326-506 Sentence denotes The inclusion criteria included: (1) patients aged between 18 and 80 years; and (2) absolute counts of peripheral blood lymphocytes < 1.1 × 109/L within 24 h of hospital admission.
T44 507-782 Sentence denotes The exclusion criteria included: (1) duration of hospital stay < 14 days or death during hospitalization; (2) pregnant or lactating women; (3) deterioration of the condition requiring ICU care within 14 days of admission; and (4) loss of consciousness during hospitalization.
T45 783-867 Sentence denotes A total of 153 patients met these criteria and were included in the study (Fig. 1 ).
T46 868-1137 Sentence denotes The diagnosis, clinical classification, treatment, and discharge criteria of COVID-19 were based on the “Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia (6th edition)” issued by the National Health and Family Planning Commission of China (NHPFC, 2020).
T47 1138-1240 Sentence denotes COVID-19 was confirmed by real-time RT-PCR for throat-swab specimens from the upper respiratory tract.
T48 1241-1295 Sentence denotes All the included patients had recovered from COVID-19.
T49 1296-1322 Sentence denotes Fig. 1 Study flow diagram.
T50 1323-1499 Sentence denotes ALC, absolute lymphocyte count; COVID-19, coronavirus disease-2019; ICU, intensive care unit; PSQI, Pittsburgh Sleep Quality Index; RCSQ, Richards-Campbell sleep questionnaire.
T51 1500-1655 Sentence denotes The study was approved by the Ethics Committee of Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (Permission number:
T52 1656-1662 Sentence denotes 0173).
T53 1663-1774 Sentence denotes Informed consent for this retrospective study was waived due to the rapid emergence of this infectious disease.
T54 1776-1796 Sentence denotes 2.2 Data collection
T55 1797-1954 Sentence denotes We reviewed the hospital's electronic medical records, nurse records, laboratory findings, and imaging examinations for all patients with confirmed COVID-19.
T56 1955-1996 Sentence denotes All data were checked by two researchers.
T57 1997-3053 Sentence denotes We collected data on age, sex, body mass index, education levels, marital status, comorbidities (chronic respiratory disease, cardiovascular and cerebrovascular diseases, and gastrointestinal, endocrine, urologic, and nervous system diseases), current smoking status, time from symptom onset to admission, signs and symptoms at disease onset, chest imaging abnormalities (unilateral or bilateral distribution of patchy shadows or ground glass opacity), vital signs on admission (respiratory rate, percutaneous oxygen saturation, heart rate, systolic blood pressure, and body temperature), laboratory parameters within 24 h of admission (blood routine, blood biochemistry and electrolytes, cardiac biomarkers, and coagulation parameters), treatment (oxygen therapy, vasoconstrictive agents, antiviral therapy, antibiotics, corticosteroids, immunoglobulin, and immunoregulatory therapy), and complications during hospitalization (acute kidney injury (AKI), acute liver dysfunction, acute cardiac injury, hyperglycemia, and hospital-acquired infection (HAI)).
T58 3054-3119 Sentence denotes AKI was identified based on the definition in the Kidney Disease:
T59 3120-3170 Sentence denotes Improving Global Outcomes statement (KDIGO, 2012).
T60 3171-3356 Sentence denotes Cardiac injury was diagnosed when the levels of serum hypersensitive cardiac troponin I exceeded the upper limit of normal (ULN), measured in the laboratory of the Wuhan Union Hospital.
T61 3357-3413 Sentence denotes Acute liver dysfunction was defined as an ALT ≥ 1 × ULN.
T62 3414-3482 Sentence denotes HAI was defined as infection acquired>48 h after hospital admission.
T63 3483-3676 Sentence denotes For patient(s) with deterioration of the condition requiring ICU care, the subsequent data regarding laboratory parameters, treatment, and complications were not included in the final analysis.
T64 3678-3699 Sentence denotes 2.3 Sleep assessment
T65 3700-3903 Sentence denotes The Richards-Campbell sleep questionnaire (RCSQ), a widely used subjective survey instrument (Nagatomo et al., 2020, Richards et al., 2000, Simons et al., 2018), was administered to assess sleep quality.
T66 3904-3988 Sentence denotes Sleep assessment was performed by telephone within 30 days after hospital admission.
T67 3989-4229 Sentence denotes The overall sleep quality was assessed within the first week (score one), second week (score two), and third week (score three) after admission using the RCSQ, since not all patients were able to accurately assess their daily sleep quality.
T68 4230-4415 Sentence denotes The RCSQ assesses the following five items on a 0–100 mm visual analog scale: perceived sleep depth, sleep latency, frequency of awakenings, latency after awakenings, and sleep quality.
T69 4416-4532 Sentence denotes The overall RCSQ score is the average value of these five items, with higher scores indicating better sleep quality.
T70 4533-4607 Sentence denotes Self-reported factors associated with disruptive sleep were also recorded.
T71 4608-4873 Sentence denotes After assessment with the RCSQ, sleep quality within two or three weeks after hospital admission was further confirmed using the Chinese version of the Pittsburgh Sleep Quality Index (PSQI), which is reliable and valid for the Chinese population (Liu et al., 1996).
T72 4874-5069 Sentence denotes The PSQI includes seven component scores: subjective sleep quality, sleep duration, sleep latency, habitual sleep efficiency, sleep disturbances, use of sleep medication, and daytime dysfunction.
T73 5070-5276 Sentence denotes The sum of the seven component scores (each ranging from 0 to 3) provides the global sleep quality score (ranging from 0 to 21), with a score greater than 7 indicating poor sleep quality (Liu et al., 1996).
T74 5277-5446 Sentence denotes Patients were divided into two groups: good-sleep group (at least two RCSQ scores ≥ 70, and PSQI ≤ 7) and poor-sleep group (at least two RCSQ scores ≤ 50, and PSQI > 7).
T75 5447-5881 Sentence denotes Patients with deterioration of their health condition requiring ICU care, or those with a duration of hospital stay < 21 days were assigned to one of the two groups based on the overall quality of their sleep within the first two weeks after hospital admission: patients with two RCSQ scores ≥ 70 and PSQI ≤ 7 were assigned to the good-sleep group and those with one RCSQ score ≤ 50 and PSQI > 7 were assigned to the poor-sleep group.
T76 5883-5896 Sentence denotes 2.4 Outcomes
T77 5897-6096 Sentence denotes The primary outcomes were: (1) recovery rate based on ALC and deterioration based on an increased NLR on day 7, 14, and 21 after admission; (2) need for ICU care within 14 days of hospital admission.
T78 6097-6226 Sentence denotes The absolute counts of peripheral blood lymphocytes and neutrophils within 24 h of hospital admission were set as baseline value.
T79 6227-6375 Sentence denotes The formula for the recovery percentage or deteriorative percentage is described as:ALCorNLRday7,day14orday21--ALCorNLRbaselineALCorNLRbaseline×100%
T80 6376-6452 Sentence denotes The secondary outcomes were: (1) HAI; and (2) total length of hospital stay.
T81 6454-6479 Sentence denotes 2.5 Statistical analysis
T82 6480-6531 Sentence denotes Categorical variables were described as number (%).
T83 6532-6673 Sentence denotes Continuous variables were described using mean (SD) if they were normally distributed, or median (interquartile range, IQR) if they were not.
T84 6674-6824 Sentence denotes Continuous variables were compared using independent group t tests when the data were normally distributed; otherwise, the Mann-Whitney test was used.
T85 6825-6956 Sentence denotes Proportions for categorical variables were compared using the χ2 test, Yates’ continuity corrected χ2 test, or Fisher’s exact test.
T86 6957-7025 Sentence denotes A two-sided P value < 0.05 was considered statistically significant.
T87 7026-7117 Sentence denotes The data collected were all analyzed using SPSS version 20.0 software (SPSS, Tokyo, Japan).