PMC:7271924 / 6148-6792 JSONTXT 12 Projects

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Id Subject Object Predicate Lexical cue
T45 0-203 Sentence denotes Due to its similarities to transferrin, which is the main iron transporting molecule in serum (22, 23), α-LF possesses iron binding capabilities (24, 25), and it can chelate two ferric irons (Fe3+) (26).
T46 204-345 Sentence denotes LF binds one ferric iron atom in each of its two lobes; however, an important attribute is that it does not release its iron, even at pH 3.5.
T47 346-469 Sentence denotes This is of importance as this property assures iron sequestration in infected tissues where the pH is commonly acidic (27).
T48 470-644 Sentence denotes In the context of its iron-binding capabilities, it means that when it binds ferric and siderophore-bound iron, it limits the availability of essential iron to microbes (27).