Id |
Subject |
Object |
Predicate |
Lexical cue |
T167 |
0-130 |
Sentence |
denotes |
The 2003 SARS-CoV strain, that also causes severe acute respiratory syndrome, attaches to host cells via host receptor ACE2 (171). |
T168 |
131-302 |
Sentence |
denotes |
This type I integral membrane protein receptor is a well-known receptor for respiratory viruses, and is abundantly expressed in tissues lining the respiratory tract (111). |
T169 |
303-392 |
Sentence |
denotes |
During COVID-19 infection, SARS-CoV-2 also enters host cells via the ACE2 receptor (172). |
T170 |
393-565 |
Sentence |
denotes |
ACE2 is highly expressed on human lung alveolar epithelial cells, enterocytes of the small intestine, and the brush border of the proximal tubular cells of the kidney (99). |
T171 |
566-713 |
Sentence |
denotes |
HSPGs are also one of the preliminary docking sites on the host cell surface and play an important role in the process of SARS-CoV cell entry (99). |
T172 |
714-858 |
Sentence |
denotes |
There is no current confirmed information that SARS-CoV-2 binds to HSPGs, however, LF blocks the infection of SARS-CoV by binding to HSPGs (99). |
T173 |
859-942 |
Sentence |
denotes |
It is not presently known whether LF binds to ACE2, but it does bind to HSPGs (99). |
T174 |
943-1079 |
Sentence |
denotes |
Whether SARS-CoV-2 also enters host cells via HPSGs in the same way, as does (the 2003) SARS-CoV clearly warrants further investigation. |