PMC:7271924 / 19168-20169 JSONTXT 12 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T153 0-23 Sentence denotes Viruses and Lactoferrin
T154 24-144 Sentence denotes LF has strong antiviral activity against a broad spectrum of both naked and enveloped DNA and RNA viruses (99, 149–151).
T155 145-335 Sentence denotes LF inhibits the entry of viral particles into host cells, either by direct attachment to the viral particles or by blocking their cellular receptors (discussed in previous paragraphs) (149).
T156 336-522 Sentence denotes Some of the viruses that LF prevents from entering host cells e.g., Herpes simplex virus (162), human papillomavirus (163), human immunodeficiency virus (HIV) (164), and rotavirus (165).
T157 523-661 Sentence denotes These viruses typically utilize common molecules on the cell membrane to facilitate their invasion into cells, including HSPGs (Figure 1).
T158 662-795 Sentence denotes HSPGs provide the first anchoring sites on the host cell surface, and help the virus make primary contact with these cells (99, 162).
T159 796-894 Sentence denotes HSPGs can be either membrane bound, or in secretory vesicles and in the extracellular matrix (86).
T160 895-1001 Sentence denotes It has been shown that LF is able to prevent the internalization of some viruses by binding to HSPGs (86).