| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T110 |
0-86 |
Sentence |
denotes |
LF plays an important role in host defense, upon its release from the neutrophil (26). |
| T111 |
87-230 |
Sentence |
denotes |
LF also enhances natural killer cell activity in immune defense (135) and can restrict the entry of the virus into host cells during infection. |
| T112 |
231-371 |
Sentence |
denotes |
As part of the host's inflammatory response, leucocytes, including neutrophils, release LF from their granules, where it is normally stored. |
| T113 |
372-528 |
Sentence |
denotes |
Activated neutrophils also release chromatin fibers, known as neutrophil extracellular traps (NETs), which trap and kill, amongst others, bacteria (1, 136). |
| T114 |
529-605 |
Sentence |
denotes |
These NETs likewise modulate both acute and chronic inflammation (137, 138). |
| T115 |
606-729 |
Sentence |
denotes |
NETs are also found in various autoimmune conditions such as rheumatoid arthritis, systemic lupus erythematosus (139, 140). |
| T116 |
730-796 |
Sentence |
denotes |
Interestingly, 106 human neutrophils can release 15 μg of LF (26). |
| T117 |
797-938 |
Sentence |
denotes |
In addition to DNA and histones, NET fibers contain extranuclear proteins and proteins such as elastase, myeloperoxidase (MPO), and LF (141). |
| T118 |
939-1082 |
Sentence |
denotes |
LF may also serve as an intrinsic inhibitor of NETs release into the circulation, and may therefore be central in controlling NETs release (1). |
| T119 |
1083-1096 |
Sentence |
denotes |
See Figure 3. |
