PMC:7267243 / 2038-7097 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T22 0-102 Sentence denotes TABLE 1 Patient characteristics of patients with COVID‐19 associated invasive pulmonary aspergillosis
T23 103-178 Sentence denotes Characteristics Patient #1 Patient #2 Patient #3 Patient #4 Patient #5
T24 179-219 Sentence denotes Gender Female Male Male Male Female
T25 220-247 Sentence denotes Age (y) 62 70 54 73 54
T26 248-303 Sentence denotes Medical history Lap. cholecystectomy for cholecystitis
T27 304-325 Sentence denotes Arterial hypertension
T28 326-361 Sentence denotes Obesity with sleep apnea (BMI 31.5)
T29 362-382 Sentence denotes Hypercholesterolemia
T30 383-416 Sentence denotes Ex‐smoker (30 PY; 5 y previously)
T31 417-501 Sentence denotes Moderate COPD (GOLD 2) Vertebral disc prolapse left L4/5, flavectomy and nucleotomy
T32 502-556 Sentence denotes Ex‐smoker (4 months previously) Arterial hypertension
T33 557-574 Sentence denotes Diabetes mellitus
T34 575-635 Sentence denotes Aneurysm coiling right A. vertebralis Arterial hypertension
T35 636-653 Sentence denotes Bullous Emphysema
T36 654-660 Sentence denotes Smoker
T37 661-681 Sentence denotes Severe COPD (GOLD 3)
T38 682-706 Sentence denotes Previous Hepatitis B No
T39 707-888 Sentence denotes Underlying immuno‐compromising condition (inhalational steroids for COPD) No (intravenous corticosteroid therapy 0.4 mg/kg/d, total of 13 d) (inhalational steroids for COPD) No
T40 889-927 Sentence denotes ICU Ward MICU MICU SICU SICU MICU
T41 928-932 Sentence denotes ARDS
T42 933-1062 Sentence denotes Horowitz‐Index, admission 12 Severe (53 mm Hg) Severe (93 mm Hg) Moderate (128 mm Hg) Severe (83 mm Hg) Moderate (167 mm Hg)
T43 1063-1105 Sentence denotes Prone positioning Yes Yes Yes Yes Yes
T44 1106-1133 Sentence denotes vvECMO Yes No No No No
T45 1134-1178 Sentence denotes Acute renal failure Yes Yes Yes Yes Yes
T46 1179-1216 Sentence denotes Dialysis No SLEDD SLEDD SLEDD No
T47 1217-1229 Sentence denotes Microbiology
T48 1230-1318 Sentence denotes Serum GM (>0.5) Negative Positive (0.7) Negative Negative 2× positive (2.7 and 1.3)
T49 1319-1340 Sentence denotes Fungal culture BALF:
T50 1341-1383 Sentence denotes Aspergillus fumigatus BALF: negative TA:
T51 1384-1410 Sentence denotes Aspergillus fumigatus TA:
T52 1411-1446 Sentence denotes Aspergillus fumigatus TA: negative
T53 1447-1525 Sentence denotes Susceptibility testing Azole susceptible a Not applicable Azole susceptible
T54 1526-1555 Sentence denotes Itraconazole MIC 0.380 (mg/L)
T55 1556-1604 Sentence denotes Voriconazole MIC 0.094 (mg/L) Azole susceptible
T56 1605-1634 Sentence denotes Itraconazole MIC 0.380 (mg/L)
T57 1635-1680 Sentence denotes Voriconazole MIC 0.094 (mg/L) Not applicable
T58 1681-1698 Sentence denotes Fungal PCR BALF:
T59 1699-1727 Sentence denotes Aspergillus fumigatus BALF:
T60 1728-1756 Sentence denotes Aspergillus fumigatus BALF:
T61 1757-1783 Sentence denotes Aspergillus fumigatus TA:
T62 1784-1819 Sentence denotes Aspergillus fumigatus TA: negative
T63 1820-1844 Sentence denotes TA/BALF GM (>0.5) BALF:
T64 1845-1867 Sentence denotes Positive (>2.5) BALF:
T65 1868-1890 Sentence denotes Positive (>2.5) BALF:
T66 1891-1936 Sentence denotes Positive (>2.5) Not available Not available
T67 1937-1954 Sentence denotes Definition of IPA
T68 1955-2165 Sentence denotes EORTC/MSG Criteria 8 Not classifiable (no host criterion) Not classifiable (no host criterion) Not classifiable (no host criterion) Not classifiable (no host criterion) Not classifiable (no host criterion)
T69 2166-2306 Sentence denotes (modified) AspICU algorithm 3 , 7 Putative Modified putative 3 (GM positivity) Putative Putative Modified putative 3 (GM positivity)
T70 2307-2315 Sentence denotes Virology
T71 2316-2366 Sentence denotes PCR TA: positive for hMPV and SARS‐CoV‐2 (E‐gene:
T72 2367-2385 Sentence denotes C t 13.29; S‐gene:
T73 2386-2442 Sentence denotes C t 12.61) TA: positive for hMPV and SARS‐CoV‐2(E‐gene:
T74 2443-2463 Sentence denotes C t 34.29; ORF1 a/b:
T75 2464-2511 Sentence denotes C t 31.47) TA positive for SARS‐CoV‐2 (E‐gene:
T76 2512-2532 Sentence denotes C t 29.74; ORF1 a/b:
T77 2533-2580 Sentence denotes C t 27.86) TA positive for SARS‐CoV‐2 (E‐gene:
T78 2581-2601 Sentence denotes C t 21.47; ORF1 a/b:
T79 2602-2667 Sentence denotes C t 20.12) TA positive for SARS‐CoV‐2 (C t values not available)
T80 2668-3244 Sentence denotes CT imaging studies Combined bilateral ground‐glass opacities with crazy paving and peripheral nodular consolidations (Video S1, Figure 1A) Ground‐glass opacities with occasional nodules (Video S2, Figure 1B) Bilateral ground‐glass opacities, nodular infiltrates with cavities and air crescent sign (Video S3, Figure 1C) Ground‐glass opacities with occasional nodules, known bullous emphysema (Video S4, Figure 1D) Ground‐glass opacities, smaller areas with crazy paving pattern, central and peripheral consolidations, and smaller nodular infiltrates (Video S5, Figure 1E)
T81 3245-3252 Sentence denotes Therapy
T82 3253-3617 Sentence denotes Antifungal treatment Voriconazole iv (6/4 mg/kg BW twice daily) Isavuconazole iv (200 mg thrice daily for 2 d; 200 mg once daily from 3 d) Caspofungin (70/50 mg once daily) followed by voriconazole iv (6/4 mg/kg BW twice daily) Voriconazole iv (6/4 mg/kg BW twice daily) Caspofungin (70/50 mg once daily) followed by voriconazole iv (6/4 mg/kg BW twice daily)
T83 3618-3880 Sentence denotes Antiviral therapy Supportive only Supportive only Hydroxychloroquine, darunavir and cobicistat at external hospital, in house changed to supportive only Supportive only Ribavirin, lopinavir/ritonavir at external hospital, in house changed to supportive only
T84 3881-3920 Sentence denotes Outcome Died Died Alive Died Alive
T85 3921-4675 Sentence denotes Abbreviations: ARDS, acute respiratory distress syndrome; BALF, bronchoalveolar lavage fluid; BW, body weight; COPD, chronic obstructive pulmonary disease; C t, threshold cycle; EORTC/MSG, European Organization for Research and Treatment of Cancer/Mycoses Study Group; GOLD, global initiative for chronic obstructive lung disease; hMPV, human metapneumovirus; IPA, invasive pulmonary aspergillosis; kg, kilogram; lap, laparoscopic; LVB, lumbar vertebral body; mg, milligram; MIC, minimal inhibitory concentration; MICU, medical ICU; ORF, open reading frame; PCR, polymerase chain reaction; PY, pack‐year history; SICU, surgical ICU; SLEDD, slow low‐efficient daily dialysis; TA, tracheal aspirate; vvECMO, veno‐venous extracorporeal membrane oxygenation.
T86 4676-4726 Sentence denotes a Antifungal susceptibility testing by VIPcheck™.
T87 4727-4728 Sentence denotes 6
T88 4729-4876 Sentence denotes John Wiley & Sons, Ltd This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response.
T89 4877-5059 Sentence denotes It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.