LitCovid-sentences  

PMC:7267243 / 12114-13820 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T143 0-13 Sentence denotes 4 DISCUSSION
T144 14-166 Sentence denotes Patients with ARDS triggered by viral infection, in particular influenza, are prone to invasive aspergillosis even in absence of prior immunodeficiency.
T145 167-326 Sentence denotes 2 , 3 We report putative IPA in five of 19 COVID‐19 patients with moderate to severe ARDS without underlying immunocompromising disease on two separate ICUs.
T146 327-412 Sentence denotes Spontaneous intrapulmonary bleeding and haemoptysis are typical complications of IPA.
T147 413-544 Sentence denotes Ground‐glass opacities characterise COVID‐19 as well as IPA, thus comprehensive microbiological evaluation can prevent missing IPA.
T148 545-809 Sentence denotes By applying strict interpretation of the host and risk factors for invasive aspergillosis according to the European Organization for Research and Treatment of Cancer/Mycoses Study Group definitions the risk of missed diagnosis increases in the COVID‐19 population.
T149 810-982 Sentence denotes 8 However, a most complicated issue in ARDS patients is to differentiate Aspergillus colonisation from invasive disease—especially as radiological imaging is non‐specific.
T150 983-1129 Sentence denotes To address this issue, a consensus project will seek to provide standard definitions for invasive fungal disease in critically ill adult patients.
T151 1130-1132 Sentence denotes 10
T152 1133-1304 Sentence denotes Our observations suggest increased risk for critically ill COVID‐19 patients to develop co‐infection with Aspergillus, which is likely to increase mortality rates further.
T153 1305-1481 Sentence denotes Therefore, testing for the presence of Aspergillus in lower respiratory secretions and galactomannan in consecutive serum samples in COVID‐19 ICU patients should be considered.
T154 1482-1484 Sentence denotes 11
T155 1485-1592 Sentence denotes Our findings need to be confirmed in clinical trials to elucidate the role of potential IPA after COVID‐19.
T156 1593-1706 Sentence denotes With this report, we aim to call attention to the critical phenomenon of COVID‐19 associated IA in ARDS patients.