PMC:7264098 / 14660-16442 JSONTXT 12 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T80 0-94 Sentence denotes Cell type Dosage Number of patients Outcome Stage of study Reference or NCT numbers#
T81 95-397 Sentence denotes MSCs (tissue source unspecified) Single dose of 1 × 106 cells per kg, IV 7 patients with severe COVID-19 pneumonia Regulation of inflammatory response (Decreased plasma C-reaction protein, reduced cytokine-secreting immune cells, reduced TNF-α, increased IL-10 and VEGF) Complete Leng et al., 2020
T82 398-485 Sentence denotes Adipose tissue-derived MSCs Two serial doses of 1.5 × 106 cells per kg, IV Estimated:
T83 486-545 Sentence denotes 100 patients N/A Phase 2; Not yet recruiting NCT04348461
T84 546-617 Sentence denotes Dental pulp stem cells 3 × 107 cells IV on day 1, 4, and 7 Estimated:
T85 618-683 Sentence denotes 20 patients N/A Phase 1 clinical trial; recruiting NCT04336254
T86 684-762 Sentence denotes Dental pulp stem cells 1 × 106 cells per kg IV on day 1, 3, and 7 Estimated:
T87 763-827 Sentence denotes 24 patients N/A Early Phase 1; Not yet recruiting NCT04302519
T88 828-926 Sentence denotes Wharton's Jelly MSCs 3 doses of 1 × 106 cells per kg IV, 3 days apart from each other Estimated:
T89 927-991 Sentence denotes 5 patients N/A Phase 1 clinical trial; recruiting NCT04313322
T90 992-1073 Sentence denotes MSCs (tissue source unspecified) 3 × 107 cells IV on day 0, 3, and 6 Estimated:
T91 1074-1139 Sentence denotes 20 patients N/A Phase 1 clinical trial; recruiting NCT04252118
T92 1140-1213 Sentence denotes Umbilical cord MSCs 9.9 × 107 cells IV on day 1, 3, 5, and 7 Estimated:
T93 1214-1279 Sentence denotes 10 patients N/A Phase 2 clinical trial; recruiting NCT04269525
T94 1280-1372 Sentence denotes Umbilical cord MSCs 0.5 × 106 cells per kg body weight IV on day 1, 3, 5, and 7 Estimated:
T95 1373-1422 Sentence denotes 48 patients N/A Not yet recruiting NCT04273646
T96 1423-1492 Sentence denotes Bone Marrow MSCs Single dose of 1 × 106 cells per kg, IV Estimated:
T97 1493-1566 Sentence denotes 20 patients N/A Phase 1 clinical trial; Not yet recruiting NCT04346368
T98 1567-1717 Sentence denotes Human embryonic stem cells derived matrix-regulatory cells 3 cohorts who receive doses of 3, 5, or 10 million cells per kg body weight IV Estimated:
T99 1718-1782 Sentence denotes 9 patients N/A Phase 1 clinical trial; recruiting NCT04331613