| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T232 |
0-109 |
Sentence |
denotes |
Among the SARS-CoV structural proteins, the spike protein has been found to elicit neutralizing antibodies24. |
| T233 |
110-273 |
Sentence |
denotes |
In this study, it was observed that of the five B-cell linear epitopes, which were predicted, four epitopes were present in the S1 domain and one in the S2 domain. |
| T234 |
274-595 |
Sentence |
denotes |
Prediction of conformational B-cell epitopes revealed that one of these (residue positions 341-505) in the spike protein incorporates two of the predicted linear epitopes (327-342 and 404-419) having good antigenicity along with a favourable IFN-γ response that enables differentiation and proliferation of the B-cells25. |
| T235 |
596-719 |
Sentence |
denotes |
Notably, an equivalent epitope (347-499) is predicted for the model generated using the SARS-CoV-1 S protein as a template. |
| T236 |
720-769 |
Sentence |
denotes |
In both cases, this epitope lies within the RBD6. |
| T237 |
770-944 |
Sentence |
denotes |
Although the epitope has two putative N-linked glycosylation sites within it at positions 330 and 332, the probability of these sites being actually glycosylated is very low. |
| T238 |
945-1040 |
Sentence |
denotes |
A major immuno-dominant epitope has been reported from SARS-CoV between residues 441 and 70026. |
| T239 |
1041-1183 |
Sentence |
denotes |
Hence, the predicted B-cell conformational epitope identified in the present study may play an important role in initiating a B-cell response. |
| T240 |
1184-1319 |
Sentence |
denotes |
Among the five linear epitopes predicted in this study, epitopes 327-342 and 1204-1219 are conserved between SARS-CoV-2 and SARS-CoV-1. |
| T241 |
1320-1387 |
Sentence |
denotes |
Epitopes 243-258, 404-419 and 413-428 are found to have variations. |
