| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T90 |
0-193 |
Sentence |
denotes |
Analysis of the relative ratio of non-synonymous to synonymous nucleotide substitutions (i.e. dN/dS ratios) revealed that exposed residues exhibited significantly higher dN/dS values (Fig. 4b). |
| T91 |
194-287 |
Sentence |
denotes |
Buried residues on SARS had mean dN/dS ratios of 0.31 compared with 2.82 for exposed resides. |
| T92 |
288-415 |
Sentence |
denotes |
Likewise, the buried residues on MERS had a calculated dN/dS ratio of 0.10 compared with exposed residues with a value of 0.45. |
| T93 |
416-746 |
Sentence |
denotes |
Furthermore, when per-site amino-acid diversities were mapped onto the fully glycosylated structural model of the respective CoV S proteins (Fig. 4c), hotspots of mutations were highlighted on the protein surface throughout the trimer revealing extensive vulnerabilities permeating through the glycan shield of SARS and MERS CoVs. |
| T94 |
747-893 |
Sentence |
denotes |
It is interesting to note the lack of amino-acid diversity on the receptor-binding domains of MERS S proteins that protrude away from the glycans. |
| T95 |
894-999 |
Sentence |
denotes |
We would suggest that this may result from the intrinsic receptor-binding functionality of these domains. |
