LitCovid-sentences  

PMC:7253233 / 2649-4886 JSONTXT 10 Projects

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Id Subject Object Predicate Lexical cue
T26 0-12 Sentence denotes Introduction
T27 13-184 Sentence denotes Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged first in Wuhan, China, in 2019 and spread rapidly worldwide as a pandemic of the twenty-first century.
T28 185-330 Sentence denotes The symptoms and disease manifestations caused by SARS-CoV-2 were named Coronavirus disease 2019 (COVID-19) by the World Health Organization [1].
T29 331-562 Sentence denotes The neurological manifestations of this disease are not well known, and there is growing evidence that the disease has effects on the central nervous system (CNS) as detailed in retrospective reports from several centers worldwide.
T30 563-709 Sentence denotes An initial retrospective case series from Wuhan, China, showed that neurological manifestations are present in patients with COVID-19 disease [2].
T31 710-906 Sentence denotes In that series, 45.5% of patients with COVID-19 disease who had severe systemic disease burden also suffered from acute cerebrovascular disease, acute encephalopathy, and skeletal muscle symptoms.
T32 907-1013 Sentence denotes These patients also had higher levels of inflammatory markers and greater evidence of multi-organ failure.
T33 1014-1147 Sentence denotes However, the study did not elucidate how many patients with encephalopathy were monitored and treated for acute symptomatic seizures.
T34 1148-1287 Sentence denotes Another series of patients were reported in Strasbourg, France, with neurological features of encephalopathy and corticospinal tract signs.
T35 1288-1450 Sentence denotes Only a small proportion of the patients (8 out of 64) had electroencephalography performed, which demonstrated diffuse slowing consistent with encephalopathy [3].
T36 1451-1589 Sentence denotes Seizures have not been directly reported as a part of COVID-19 disease outside of patients with previously known brain injury or epilepsy.
T37 1590-1847 Sentence denotes There are several barriers to electrographically monitoring patients with SARS-CoV-2 infection such as prone positioning for respiratory compromise as well as the contamination risk which obviates a need for minimizing procedures in this patient population.
T38 1848-1972 Sentence denotes Neurointensivists and neurologists are often consulted for severe COVID-19 patients that present with neurological features.
T39 1973-2237 Sentence denotes In this report, we describe two patients who were electrographically monitored for acute encephalopathy and seizure-like activity, in the setting of normal brain imaging and who were found to have acute symptomatic seizures associated with severe COVID-19 disease.