| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T861 |
0-229 |
Sentence |
denotes |
To further evaluate whether our ability to detect ACE2+ cells was an artifact of sequencing depth, we compared the number of ACE2+ cells in a cluster to the mean number of reads across all cells in that same cluster (Figure S6E). |
| T862 |
230-563 |
Sentence |
denotes |
We did not observe any significant correlation: the ileum cell cluster with the highest number of ACE2+ cells had the lowest sequencing depth of all ileum clusters, and the lung cell cluster with the highest number of ACE2+ cells was approximately average in its read depth (on a log-log scale, Pearson’s r = −0.31, non-significant). |
| T863 |
564-1095 |
Sentence |
denotes |
Further, when comparing ACE2+ cells to ACE2- cells within a given tissue, we did not observe a positive correlation between read depth and ACE2 status (i.e., mean ± standard error of the mean, SEM, reads among all lung cells = 28,512 ± 344; mean ± SEM reads among ACE2+ lung cells = 28,553 ± 2,988; mean ± SEM reads among all ileum cells = 14,864 ± 288; mean ± SEM reads among ACE2+ ileum cells = 10,591 ± 441, full statistics on cell depth among ACE2+ cells compared to ACE2- cells of the same cell type can be found in Table S9). |
| T864 |
1096-1239 |
Sentence |
denotes |
Thus, we can be confident that the observed differences in ACE2+ proportions across clusters are not driven by differences in sequencing depth. |
