Id |
Subject |
Object |
Predicate |
Lexical cue |
T45 |
0-192 |
Sentence |
denotes |
Compounds of the main herb in formula MSXG, SGMH, XCH, WLS and Others were searched in TCMSP [13], and screened based on drug-likeness (DL) ≥0.18 [14] and oral bioavailability (OB) ≥30 % [15]. |
T46 |
193-293 |
Sentence |
denotes |
Then, the corresponding Pubchem CIDs of the compounds were retrieved from the Pubchem database [16]. |
T47 |
294-489 |
Sentence |
denotes |
Finally, BATMAN-TCM [17], an bioinformatics analysis tool for studying TCM’s molecular mechanisms, was used to identify potential target genes of the active components (uploaded by Pubchem CIDs). |
T48 |
490-570 |
Sentence |
denotes |
To make the results more credible, we set the cutoff score ≥ 30 as the standard. |
T49 |
571-761 |
Sentence |
denotes |
Finally, to discovery the co-differentially presented targets in the five formulae, we conducted pan-formula analysis using Venn diagrams (http://bioinformatics.psb.ugent.be/webtools/Venn/). |