LitCovid-sentences  

PMC:7247521 / 29019-31631 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T216 0-525 Sentence denotes The application of COVID-19 docking server and Discovery Studio software elucidated the interactions between the 20 lead-likeness compounds (S1, W5, MX17, MX16, W11, M5, XO1, MXO1, SO1, WO1, X4, MX8, M3, S5, SX1, O1, X2, X1, O2, MS1) and the 10 nonstructural and 2 structural proteins (Mpro, PLpro, nsp12 [RdRp with RNA], nsp12 [RdRp without RNA], nsp13 [Helicase ADP site], nsp13 [Helicase NCB site], nsp14 [ExoN], nsp14 [N7-MTase], nsp15 [endoribonuclease], nsp16 [2′-O-MTase], N protein NCB site, E protein [ion channel]).
T217 526-580 Sentence denotes The docking scores were depicted in Table 3, Table 4 .
T218 581-725 Sentence denotes The smaller of docking score, the lower of energy would be required, which means the binding between the compounds and the targets are stronger.
T219 726-803 Sentence denotes There are 9 compounds presenting better bonding ability than other compounds.
T220 804-886 Sentence denotes Table 3 Docking score between specific ingredients of QFPD and 2019-nCov proteins.
T221 887-929 Sentence denotes Molecule M3 M5 S1 S5 W11 W5 X1 X2 X4 O1 O2
T222 930-998 Sentence denotes Main Protease −7.7 −7.3 −6.8 −6.9 −7.2 −7.5 −7.1 −7.9 −7.3 −7.1 −7.4
T223 999-1070 Sentence denotes Papain-like protease −8.7 −8.5 −9.9 −7.7 −8 −8 −8.4 −8.7 −8.2 −8.6 −8.2
T224 1071-1139 Sentence denotes RdRp with RNA −8.4 −8.5 −8.5 −8.3 −9.1 −9.1 −8.4 −8.2 −8.2 −8.3 −8.6
T225 1140-1211 Sentence denotes RdRp without RNA −6.8 −6.8 −6.9 −6.8 −6.7 −6.9 −7.1 −7.2 −6.5 −7.3 −7.1
T226 1212-1280 Sentence denotes Helicase ADP site −6.3 −6.3 −7.3 −6.5 −6 −6 −6.3 −6.5 −6.2 −6.1 −6.5
T227 1281-1353 Sentence denotes Helicase NCB site −7.9 −6.9 −7.2 −7.1 −7.2 −7.2 −7.4 −7.5 −7.3 −7.4 −7.4
T228 1354-1420 Sentence denotes Nsp14(ExoN) −6.8 −6.6 −6.3 −6.4 −6.9 −6.8 −6.7 −6.9 −6.4 −6.6 −6.9
T229 1421-1489 Sentence denotes Nsp14(N7-MTase) −8.8 −8.1 −8.5 −7.5 −8.4 −8.4 −8.3 −8.5 −8 −8.3 −8.5
T230 1490-1568 Sentence denotes Nsp15(endoribonuclease) −6.6 −6.3 −6.3 −5.9 −6.2 −6.2 −6.2 −6.3 −6.2 −6.4 −6.4
T231 1569-1641 Sentence denotes Nsp16(2′-O-MTase) −7.5 −7.4 −7.5 −7.2 −8.2 −8.2 −7.7 −7.9 −7.7 −7.9 −8.4
T232 1642-1711 Sentence denotes N protein NCB site −7.6 −7.5 −7.8 −7.6 −7.6 −7.6 −8 −8 −7.5 −7.6 −7.6
T233 1712-1787 Sentence denotes E protein(ion channel) −8.1 −7 −7.8 −6.7 −6.4 −6.4 −7.2 −7.3 −7.2 −7.1 −6.8
T234 1788-1816 Sentence denotes M: MXSG, S: SGMH, X: XCH, O:
T235 1817-1824 Sentence denotes Others.
T236 1825-1916 Sentence denotes Table 4 Evaluation of the effect of QFPD on the robustness disturbance of COVID-19 network.
T237 1917-1960 Sentence denotes Topology MXSG SGMH XCH WLS Others BXTM YDBF
T238 1961-2006 Sentence denotes DTS 25.66 26.71 21.02 17.64 23.16 14.52 22.71
T239 2007-2051 Sentence denotes AC −4.63 −5.21 −3.02 −3.49 −5.38 −2.32 −3.78
T240 2052-2094 Sentence denotes APL 13.35 13.40 9.96 6.49 10.66 4.59 11.17
T241 2095-2140 Sentence denotes CoC −1.44 −1.64 −1.59 −1.30 −1.23 −1.15 −1.25
T242 2141-2186 Sentence denotes ClC −6.24 −6.46 −6.45 −6.36 −5.88 −6.46 −6.52
T243 2187-2372 Sentence denotes Average connectivity (AC), Connection centrality (CoC), Closeness centrality (ClC): the larger the quotient is, the more stable the network and, the less the influence made by the drug.
T244 2373-2548 Sentence denotes Disturbance total score (DTS), Average length of shortest path (APL), : the larger the quotient is, the less stable the network and, the larger the influence made by the drug.
T245 2549-2580 Sentence denotes Negative control formula: BXTM.
T246 2581-2612 Sentence denotes Positive control formula: YDBF.