LitCovid-sentences  

PMC:7245254 / 61-1737 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T3 0-22 Sentence denotes Background and Purpose
T4 23-138 Sentence denotes Patients with the Coronavirus Disease of 2019 (COVID-19) are at increased risk for thrombotic events and mortality.
T5 139-216 Sentence denotes Various anticoagulation regimens are now being considered for these patients.
T6 217-357 Sentence denotes Anticoagulation is known to increase the risk for adverse bleeding events, of which intracranial hemorrhage (ICH) is one of the most feared.
T7 358-512 Sentence denotes We present a retrospective study of 33 patients positive for COVID-19 with neuroimaging-documented ICH and examine anticoagulation use in this population.
T8 514-521 Sentence denotes Methods
T9 522-635 Sentence denotes Patients over the age of 18 with confirmed COVID-19 and radiographic evidence of ICH were included in this study.
T10 636-730 Sentence denotes Evidence of hemorrhage was confirmed and categorized by a fellowship trained neuroradiologist.
T11 731-892 Sentence denotes Electronic health records were analyzed for patient information including demographic data, medical history, hospital course, laboratory values, and medications.
T12 894-901 Sentence denotes Results
T13 902-1023 Sentence denotes We identified 33 COVID-19 positive patients with ICH, mean age 61.6 years (range 37–83 years), 21.2% of whom were female.
T14 1024-1139 Sentence denotes Parenchymal hemorrhages with mass effect and herniation occurred in 5 (15.2%) patients, with a 100% mortality rate.
T15 1140-1345 Sentence denotes Of the remaining 28 patients with ICH, 7 (25%) had punctate hemorrhages, 17 (60.7%) had small- moderate size hemorrhages, and 4 (14.3%) had a large single site of hemorrhage without evidence of herniation.
T16 1346-1506 Sentence denotes Almost all patients received either therapeutic dose anticoagulation (in 22 [66.7%] patients) or prophylactic dose (in 3 [9.1] patients) prior to ICH discovery.
T17 1508-1519 Sentence denotes Conclusions
T18 1520-1676 Sentence denotes Anticoagulation therapy may be considered in patients with COVID-19 though the risk of ICH should be taken into account when developing a treatment regimen.