| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T216 |
0-51 |
Sentence |
denotes |
Antibody response to RBD is viral species-specific. |
| T217 |
52-186 |
Sentence |
denotes |
Effectively, none of the found SARS-CoV-2 antibodies nor the infected plasma cross-reacted with RBDs from either SARS-CoV or MERS-CoV. |
| T218 |
187-290 |
Sentence |
denotes |
In a study, 206 monoclonal antibodies specific to the RBD SARS-CoV-2 were identified in eight patients. |
| T219 |
291-443 |
Sentence |
denotes |
These mAbs are different in: antibody heavy and light chains, antibody clones, CDR3 length… which lead to different binding and neutralizing capacities. |
| T220 |
444-535 |
Sentence |
denotes |
ACE2 is out-competed with almost 100% efficacity by some mAbs such as P2B-2F6 and P2C-1F11. |
| T221 |
536-699 |
Sentence |
denotes |
Interestingly the latter and a moderate antibody P2C-1C10 seems to target the different epitopes, and they could be combined for synergistic antiviral effect [96]. |
| T222 |
700-867 |
Sentence |
denotes |
CR3022, a SARS-CoV RBD-specific antibody, can bind strongly with a kd of 6.3 nM to an epitope on RBD that does not overlap with the SARS-Cov-2 ACE-2 binding site [34]. |
| T223 |
868-940 |
Sentence |
denotes |
Despite its strong binding, CR3022 could not neutralize SARS-CoV-2 [97]. |
