Id |
Subject |
Object |
Predicate |
Lexical cue |
T185 |
0-213 |
Sentence |
denotes |
SARS-CoV-2 nAbs could be detected in patients from 10 to 15 days after symptoms onset and the positive rate for IgG reached close to 100% around 20 days [81,82] with the highest level during day 31–40 since onset. |
T186 |
214-307 |
Sentence |
denotes |
Some patients (5.7%) had neutralizing Abs titers under the detectable level (ID50: <40) [83]. |
T187 |
308-398 |
Sentence |
denotes |
The level of IgG antibodies was different between gender, age and clinical classification. |
T188 |
399-487 |
Sentence |
denotes |
The average IgG antibody level in female patients was higher than in male patients [84]. |
T189 |
488-591 |
Sentence |
denotes |
Patient over 40 years old developed higher levels of SARS-CoV-2 specific nAbs than the younger persons. |
T190 |
592-671 |
Sentence |
denotes |
Patients with a worse clinical classification had a higher antibody titer [83]. |
T191 |
672-751 |
Sentence |
denotes |
This remark is useful to select a research candidate and to save research time. |
T192 |
752-888 |
Sentence |
denotes |
The passive antibody therapy, such as plasma fusion containing polyclonal antibodies from COVID-19 neutralized patients has been tested. |
T193 |
889-1016 |
Sentence |
denotes |
This method was tested as an option to treat other viruses such as influenza, Ebola or SARS-CoV [[85], [86], [87], [88], [89]]. |
T194 |
1017-1127 |
Sentence |
denotes |
The lack of human sera, and the possibility of contamination with other infectious agents limit this strategy. |
T195 |
1128-1233 |
Sentence |
denotes |
However, several groups have reported some positive results demonstrating the potential of this approach. |
T196 |
1234-1434 |
Sentence |
denotes |
After one dose of 200 mL of convalescent plasma derived from recently recovered donors with the neutralizing antibody titers above 1:640, the patients with SARS-CoV-2 positive revealed an improvement. |
T197 |
1435-1512 |
Sentence |
denotes |
Among ten patients, seven patients were virus-negative post transfusion [90]. |
T198 |
1513-1692 |
Sentence |
denotes |
Whereas in another study, among 5 patients received transfusion with convalescent plasma with a neutralization titer >40, 3 have been discharged from the hospital (length of stay: |
T199 |
1693-1779 |
Sentence |
denotes |
53, 51, and 55 days), and 2 are in stable condition at 37 days after transfusion [91]. |
T200 |
1780-1898 |
Sentence |
denotes |
More studies might brighter this approach but evaluation in clinical trials are also still far from a bold conclusion. |