PMC:7243768 / 9791-13336 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T67 0-35 Sentence denotes 4.1 SARS-CoV – cardiovascular risk
T68 36-128 Sentence denotes It was reported that SARS induced myocardial infarction and acute coronary syndrome [31,32].
T69 129-260 Sentence denotes A small group of 75 patients infected with SARS had shown that 2 of the five patients died due to acute myocardial infarction [32].
T70 261-498 Sentence denotes In another study which was conducted among 46 patients infected with SARS indicated that there were no significant changes in the initial stages of infection and, after 30 days, didn't show any risks related to the cardiovascular system.
T71 499-805 Sentence denotes In another study conducted on 121 patients, it was reported that patients had other comorbidities such as cardiovascular diseases, hypotension, and transient cardiomegaly, particularly tachycardia and transient paroxysmal atrial fibrillation and most importantly tachycardia [33] (represented in Table 1 ).
T72 806-941 Sentence denotes Table 1 Differentiating SARS-CoV, MERS-CoV, and SARS-CoV-2 based on the impact of manifestations posed by them at various organ levels.
T73 942-977 Sentence denotes Target SARS-CoV MERS-CoV SARS-CoV-2
T74 978-1019 Sentence denotes ACE2 receptor DPP4 receptor ACE2 receptor
T75 1020-1022 Sentence denotes 1.
T76 1023-1400 Sentence denotes Heart Hypotension, transient cardiomegaly, tachycardia, transient paroxysmal atrial fibrillation, myocardial infarction, acute coronary syndrome Elevated troponin levels, a chronic severe 3-vessel disease with no acute vessel closure characterized by coronary angiography Decreased levels of ACE2 receptor and increased troponin, resulting in cardiac arrest and cardiac injury.
T77 1401-1403 Sentence denotes 2.
T78 1404-1729 Sentence denotes Lungs Hepatization, severe lung consolidation, edema with pleural effusion, mucopurulent material in the tracheobronchial tree, focal hemorrhage, alveolar and septal fibrosis, edema, alveolar hemorrhage, fibrin exudation in alveolar spaces, hyaline membrane formation, and extreme bronchiolar injury indicate the acute phase.
T79 1730-2146 Sentence denotes Acute respiratory distress syndrome, septic shock, the mild upper respiratory illness may result in swiftly growing pneumonitis, respiratory failure Severe acute respiratory syndrome (SARS), acute respiratory distress syndrome (ARDS), focal reactive hyperplasia of pneumocytes with patchy inflammatory cellular infiltration, edema, multinucleated giant cells, protruding hyaline membranes, and proteinaceous exudate.
T80 2147-2149 Sentence denotes 3.
T81 2150-2231 Sentence denotes Kidney Acute renal impairment – Proteinuria, hematuria, acute kidney injury (AKI)
T82 2232-2234 Sentence denotes 4.
T83 2235-2661 Sentence denotes Liver Hepatitis, liver injury characterized by elevated ALT, and AST levels Disintegrated death of hepatocytes in the hepatic sinus, penetration of large amounts of activated macrophages and Kupffer cells, elevated pro-inflammatory cytokine responses, and lobular lymphocytes infiltrate, mild cellular hydropic degeneration in hepatic parenchyma and mild portal tract and liver damage indicated by elevated ALT and AST levels.
T84 2662-2726 Sentence denotes Liver injury characterized by elevated ALT, GGT, and AST levels.
T85 2727-2754 Sentence denotes Decreased bilirubin levels.
T86 2755-2757 Sentence denotes 5.
T87 2758-2877 Sentence denotes Gastrointestinal tract – – Viral load found in the cytoplasm of epithelia of duodenum and rectum, nausea, and diarrhea.
T88 2878-2880 Sentence denotes 6.
T89 2881-3545 Sentence denotes Central nervous system Vision-related issues, the chemotactic attraction of immune cells by the infected brain cells, the presence of a chemokine called Mig found in the patient's brain Fever, vomiting, confusion and ataxia, bilateral basal ganglia, deep white matter, large area of hypodensity in the proximal half of the corpus callosum up to the mid part of his body and interval multiple patchy hypodensities bilaterally in the periventricular, acute infarction, and bilaterally in the deep watershed and the parasagittal region as well as scattered foci in the cortical and subcortical regions of the temporal and parietal lobes Nausea, vomiting, and headache