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LitCovid-sentences

PMC:7243768 / 22489-24071 JSON TXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id	Subject	Object	Predicate	Lexical cue
T152	0-26	Sentence	denotes	5.2 MERS-CoV-liver injury
T153	27-174	Sentence	denotes	The patients infected by MERS-CoV were also presented with alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels above normal.
T154	175-325	Sentence	denotes	Besides the elevated liver enzymes, the albumin levels were decreased, which serves as an indicator of the severity of the disease [[67], [68], [69]].
T155	326-418	Sentence	denotes	The MERS-CoV enters the host cell through the DPP-4 receptor and spreads the infection [70].
T156	419-513	Sentence	denotes	The liver is the main organ that expresses high levels of Dipeptidyl peptidase 4 (DPP-4) [71].
T157	514-880	Sentence	denotes	This was experimentally proved by infecting the transgenic mice expressing hDPP4 with MERS-CoV which indicated that the liver injury had taken place on the 5th day of the infection as evidenced by the pathological manifestations such as disintegrated death of hepatocytes in the hepatic sinus, penetration of large amounts of activated macrophages and Kupffer cells.
T158	881-1035	Sentence	denotes	The changes related to fat metabolism were observed on the 9th day of infection, and the liver cell necrosis was quite less [72] (represented in Table 1).
T159	1036-1249	Sentence	denotes	The histopathological findings of the hepatic tissue during MERS-CoV infection include infiltration of lobular lymphocytes, mild cellular hydropic degeneration in hepatic parenchyma, and mild portal tract [73,74].
T160	1250-1400	Sentence	denotes	During the acute phase of infection, the levels of pro-inflammatory cytokines such as TNF-α, IFN-γ, IL-17, and IL-15 were significantly elevated [75].
T161	1401-1582	Sentence	denotes	But the question of whether liver injury initiated is due to the viral-mediated pathogenesis or due to the drugs that have been used during the viral infection remains elusive [37].