PMC:7243768 / 14888-16386 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T103 0-24 Sentence denotes 4.4 SARS-CoV-liver risk
T104 25-174 Sentence denotes The elevated ALT and AST levels indicate liver damage, which was evident in SARS-CoV infected individuals right from the initial stages of infection.
T105 175-281 Sentence denotes Also, the bilirubin levels were elevated, and the albumin levels decreased, indicating the hepatic damage.
T106 282-393 Sentence denotes Also, the degree of hepatic damage depends on the severity of the disease [[37], [38], [39], [40], [41], [42]].
T107 394-522 Sentence denotes The ACE2 receptor, which is responsible for the SARS-CoV entry, is widely distributed on the hepatic tissue's endothelial cells.
T108 523-672 Sentence denotes The existence of the viral genome in the vascular endothelial cells and parenchymal cells indicates that SARS-CoV infects the lungs and other organs.
T109 673-772 Sentence denotes The presence of viral load in the hepatic cells was confirmed using RT-PCR technique [12,14,37,43].
T110 773-1012 Sentence denotes Also, the SARS-CoV specific protein 7a has shown to be responsible for causing apoptosis not only in the lungs but also in the other organs, including the liver through the caspase-dependent pathway, thereby resulting in liver injury [44].
T111 1013-1138 Sentence denotes The levels of pro-inflammatory cytokines were increased, which indicates that SARS-CoV also results in the inflammation [42].
T112 1139-1364 Sentence denotes It was also noted that SARS-CoV patients with predisposed hepatitis were more vulnerable to severe SARS-CoV infection due to the reason that the hepatitis virus exhibits exaggerated replication during SARS-CoV infection [45].
T113 1365-1498 Sentence denotes Sometimes, the drugs used to treat viral infections may also lead to liver injury, which is termed as drug-induced liver injury [37].