Id |
Subject |
Object |
Predicate |
Lexical cue |
T32 |
0-114 |
Sentence |
denotes |
Table 1 Selected AASLD, APASL, and EASL Recommendations for Liver Disease Management During the COVID‐19 Pandemic |
T33 |
115-150 |
Sentence |
denotes |
Recommendations AASLD APASL EASL |
T34 |
151-225 |
Sentence |
denotes |
Limit nosocomial transmission Prioritize patients to limit in‐person care |
T35 |
226-372 |
Sentence |
denotes |
On arrival, screen patients for COVID‐19 symptoms, exposures; if suggestive of COVID‐19, refer care per clinic’s protocol for symptomatic patients |
T36 |
373-419 |
Sentence |
denotes |
Use telemedicine alternatives for routine care |
T37 |
420-468 |
Sentence |
denotes |
Reduce routine laboratory and imaging monitoring |
T38 |
469-501 |
Sentence |
denotes |
Prescribe 90 days of medications |
T39 |
502-566 |
Sentence |
denotes |
Cancel all elective/nonurgent endoscopic procedures and biopsies |
T40 |
567-609 |
Sentence |
denotes |
Limit in‐clinic evaluations for transplant |
T41 |
610-668 |
Sentence |
denotes |
Limit clinical trial activity to essential clinical trials |
T42 |
669-715 |
Sentence |
denotes |
Limit HCWs providing care or on patient rounds |
T43 |
716-799 |
Sentence |
denotes |
HCWs follow recommendations for PPE Use telemedicine alternatives for routine care |
T44 |
800-843 |
Sentence |
denotes |
Minimize number of HCWs caring for patients |
T45 |
844-885 |
Sentence |
denotes |
Minimize number of HCWs on patient rounds |
T46 |
886-943 |
Sentence |
denotes |
Cancel elective, nonurgent endoscopies and liver biopsies |
T47 |
944-1017 |
Sentence |
denotes |
HCWs follow recommendations for PPE Limit in‐person care to urgent cases |
T48 |
1018-1060 |
Sentence |
denotes |
Remodel clinic space for social distancing |
T49 |
1061-1122 |
Sentence |
denotes |
Use telemedicine for routine care; postpone specialist visits |
T50 |
1123-1183 |
Sentence |
denotes |
Reduce frequency of laboratory monitoring and obtain locally |
T51 |
1184-1219 |
Sentence |
denotes |
HCWs follow recommendations for PPE |
T52 |
1220-1485 |
Sentence |
denotes |
Evaluate and care for patients with COVID‐19 for liver disease Prioritize for COVID‐19 testing: (1) patients with cirrhosis, (2) patients with CLD receiving immunosuppressive medications, and (3) patients with new‐onset encephalopathy or other acute decompensation |
T53 |
1486-1524 |
Sentence |
denotes |
Regularly monitor liver biochemistries |
T54 |
1525-1647 |
Sentence |
denotes |
Consider non‐COVID‐19 etiologies for liver disease: (1) exacerbation of preexisting CLD or (2) drug‐induced hepatotoxicity |
T55 |
1648-1697 |
Sentence |
denotes |
Use acetaminophen 2 g/day as preferred medication |
T56 |
1698-1748 |
Sentence |
denotes |
Use nonsteroidal anti‐inflammatory drugs as needed |
T57 |
1749-1876 |
Sentence |
denotes |
Consult the University of Liverpool document to assess possible drug interactions Follow WHO guidelines for COVID‐19 diagnosis |
T58 |
1877-1934 |
Sentence |
denotes |
Consider NAFLD as a prognostic factor for severe COVID‐19 |
T59 |
1935-1982 |
Sentence |
denotes |
Screen patients for hepatitis B surface antigen |
T60 |
1983-2066 |
Sentence |
denotes |
Consider HBV prophylaxis prior to use of anti‐IL‐6, other immunosuppressive therapy |
T61 |
2067-2116 |
Sentence |
denotes |
Monitor liver function tests of patients with CLD |
T62 |
2117-2157 |
Sentence |
denotes |
Be alert to possible drug hepatotoxicity |
T63 |
2158-2237 |
Sentence |
denotes |
Decompensated CLD and ALT >5 times ULD contraindications for remdesivir therapy |
T64 |
2238-2397 |
Sentence |
denotes |
Prioritize persons with CLD for clinical trials Test for COVID‐19 patients with acute decompensation or acute‐on‐chronic liver and per institution’s practices |
T65 |
2398-2476 |
Sentence |
denotes |
Persons with NAFLD likely to have comorbidity risk factors for severe COVID‐19 |
T66 |
2477-2551 |
Sentence |
denotes |
Consider patients with CLD/COVID‐19 for early admission and clinical trial |
T67 |
2552-2599 |
Sentence |
denotes |
Use acetaminophen (2–3 g/day is generally safe) |
T68 |
2600-2649 |
Sentence |
denotes |
Limit use of nonsteroidal anti‐inflammatory drugs |
T69 |
2650-2760 |
Sentence |
denotes |
Test for COVID‐19 patients with acute decompensation or acute‐on‐chronic liver and per institution’s practices |
T70 |
2761-2839 |
Sentence |
denotes |
Persons with NAFLD likely to have comorbidity risk factors for severe COVID‐19 |
T71 |
2840-2914 |
Sentence |
denotes |
Consider patients with CLD/COVID‐19 for early admission and clinical trial |
T72 |
2915-2962 |
Sentence |
denotes |
Use acetaminophen (2–3 g/day is generally safe) |
T73 |
2963-3012 |
Sentence |
denotes |
Limit use of nonsteroidal anti‐inflammatory drugs |
T74 |
3013-3102 |
Sentence |
denotes |
Manage hepatitis B; hepatitis C Continue HBV and HCV treatment of patients with COVID‐19 |
T75 |
3103-3190 |
Sentence |
denotes |
Proceed with HBV and HCV treatment in patients without COVID‐19 as clinically warranted |
T76 |
3191-3330 |
Sentence |
denotes |
Do not consider HBV treatment in patients with COVID‐19 unless flare is suspected Continue HBV and HCV treatment of patients with COVID‐19 |
T77 |
3331-3418 |
Sentence |
denotes |
Proceed with HBV and HCV treatment in patients without COVID‐19 as clinically warranted |
T78 |
3419-3500 |
Sentence |
denotes |
Do not consider HBV treatment in patients with COVID‐19 unless flare is suspected |
T79 |
3501-3572 |
Sentence |
denotes |
Document discussion with patient regarding CLD diagnosis and management |
T80 |
3573-3685 |
Sentence |
denotes |
Manage patients with HCC Continue HCC surveillance schedule for high‐risk subjects; 2‐month delay is acceptable |
T81 |
3686-3765 |
Sentence |
denotes |
Document discussion of risks and benefits of delaying surveillance with patient |
T82 |
3766-3852 |
Sentence |
denotes |
Proceed with HCC treatments as appropriate Continue therapy for non‐COVID‐19 patients |
T83 |
3853-3994 |
Sentence |
denotes |
For patients with HCC with COVID‐19, postpone elective transplant and resection surgery, withhold immunotherapy Maintain care per guidelines |
T84 |
3995-4031 |
Sentence |
denotes |
Admit early if COVID‐19 is diagnosed |
T85 |
4032-4065 |
Sentence |
denotes |
Consider postponing HCC therapies |
T86 |
4066-4156 |
Sentence |
denotes |
Manage pretransplant and posttransplant patients Screen donors and recipient for COVID‐19 |
T87 |
4157-4228 |
Sentence |
denotes |
Do not postpone transplants (an essential medical service, CMS Tier 3b) |
T88 |
4229-4298 |
Sentence |
denotes |
Notify patients of possible extended waiting times on transplant list |
T89 |
4299-4391 |
Sentence |
denotes |
Have low threshold for admitting patients on transplant waiting list diagnosed with COVID‐19 |
T90 |
4392-4506 |
Sentence |
denotes |
For posttransplant patients with moderate COVID‐19, consider reduction of immunosuppression therapy as appropriate |
T91 |
4507-4625 |
Sentence |
denotes |
Do not reduce immunosuppressive therapy in patients with mild COVID‐19 disease Test donors and recipient for COVID‐19 |
T92 |
4626-4680 |
Sentence |
denotes |
Limit transplant listing to emergency and urgent cases |
T93 |
4681-4768 |
Sentence |
denotes |
Look for SARS‐COV‐2 prior to organ procurement; defer donors with evidence of infection |
T94 |
4769-4842 |
Sentence |
denotes |
Consider specific COVD‐19 consent for patients on transplant waiting list |
T95 |
4843-4956 |
Sentence |
denotes |
For posttransplant patient with moderate COVID‐19, consider reduction of immunosuppression therapy as appropriate |
T96 |
4957-5065 |
Sentence |
denotes |
Do not reduce immunosuppressive therapy in patients with mild COVID‐19 disease Maintain care per guidelines |
T97 |
5066-5139 |
Sentence |
denotes |
Limit transplantation listings to patients with poor short‐term prognosis |
T98 |
5140-5175 |
Sentence |
denotes |
Vaccinate against pneumonia and flu |
T99 |
5176-5221 |
Sentence |
denotes |
Avoid reductions in immunosuppressive therapy |
T100 |
5222-5292 |
Sentence |
denotes |
Do not reduce immunosuppressive therapy in patients with mild COVID‐19 |
T101 |
5293-5440 |
Sentence |
denotes |
John Wiley & Sons, Ltd This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. |
T102 |
5441-5623 |
Sentence |
denotes |
It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency. |