PMC:7228253 / 68-2797 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T3 0-254 Sentence denotes The Coronavirus Disease 2019 (COVID‐19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is not only spreading throughout China but has reached more than 20 countries and has already posed threats to global health and economy.
T4 255-334 Sentence denotes So far, the number of people infected in China has climbed to more than 70 000.
T5 335-396 Sentence denotes Of them, at least 3019 healthcare workers have been infected.
T6 397-501 Sentence denotes However, the specific causes of infection among healthcare workers in hospital environments are unclear.
T7 502-613 Sentence denotes It has been confirmed that COVID‐19 is mainly transmitted through both respiratory droplets and direct contact.
T8 614-683 Sentence denotes Aerosols are another possible transmission route requiring attention.
T9 684-823 Sentence denotes In February 2020, a report in The Lancet raised the issue that ocular surfaces may be a potential target for SARS‐CoV‐2 invasion (Lu et al.
T10 824-830 Sentence denotes 2020).
T11 831-906 Sentence denotes However, two recent studies do not fully support this assumption (Li et al.
T12 907-924 Sentence denotes 2020; Zhou et al.
T13 925-950 Sentence denotes 2020, unpublished paper).
T14 951-1124 Sentence denotes The reason is that although a small number of COVID‐19 patients have conjunctivitis, not all of them show positive test of SARS‐CoV‐2 nucleic acid in conjunctival sac swabs.
T15 1125-1362 Sentence denotes In addition, some patients did not have conjunctivitis despite positive test results for the SARS‐CoV‐2 nucleic acid in their conjunctiva sac swabs (Dr. Yanping Song from Wuhan City, China, the outbreak area in China, unpublished paper).
T16 1363-1605 Sentence denotes Interestingly, the medical history of the clinical physicians with COVID‐19 revealed that neither of them used eye goggles when examining (physician 1) and intubating infected patients (a high‐risk procedure to produce aerosol) (physician 2).
T17 1606-1898 Sentence denotes Studies show that, like the severe acute respiratory syndrome coronavirus (SARS‐CoV) that caused SARS, SARS‐CoV‐2 binds to human angiotensin‐enzyme II (ACE2), using it as a cell entry receptor to invade respiratory and lung epithelium through the spike (S) protein (Zhou et al., 2020a,2020b).
T18 1899-2091 Sentence denotes However, ACE2 is mainly expressed in posterior tissues of the eye, such as the retina and the retinal pigment epithelium, not in the human conjunctival and corneal epithelium (Choudhary et al.
T19 2092-2098 Sentence denotes 2017).
T20 2099-2187 Sentence denotes We presume that these previous studies ignored the characteristics of lacrimal drainage.
T21 2188-2240 Sentence denotes Tears are constantly renewed by the lacrimal system.
T22 2241-2397 Sentence denotes Therefore, we speculate that the virus enters the tears through droplets, which may pass through the nasolacrimal ducts and then into the respiratory tract.
T23 2398-2572 Sentence denotes Combined with all this information, we assert that, when coming into contact with confirmed or suspected cases of COVID‐19, healthcare workers should wear eye safety goggles.
T24 2573-2659 Sentence denotes This should become one of the critical measures for preventing the spread of COVID‐19.
T25 2660-2729 Sentence denotes The authors hope this topic is helpful for work in the outbreak area.