PMC:7228253 / 59-2797 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T2 0-7 Sentence denotes Editor,
T3 9-263 Sentence denotes The Coronavirus Disease 2019 (COVID‐19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is not only spreading throughout China but has reached more than 20 countries and has already posed threats to global health and economy.
T4 264-343 Sentence denotes So far, the number of people infected in China has climbed to more than 70 000.
T5 344-405 Sentence denotes Of them, at least 3019 healthcare workers have been infected.
T6 406-510 Sentence denotes However, the specific causes of infection among healthcare workers in hospital environments are unclear.
T7 511-622 Sentence denotes It has been confirmed that COVID‐19 is mainly transmitted through both respiratory droplets and direct contact.
T8 623-692 Sentence denotes Aerosols are another possible transmission route requiring attention.
T9 693-832 Sentence denotes In February 2020, a report in The Lancet raised the issue that ocular surfaces may be a potential target for SARS‐CoV‐2 invasion (Lu et al.
T10 833-839 Sentence denotes 2020).
T11 840-915 Sentence denotes However, two recent studies do not fully support this assumption (Li et al.
T12 916-933 Sentence denotes 2020; Zhou et al.
T13 934-959 Sentence denotes 2020, unpublished paper).
T14 960-1133 Sentence denotes The reason is that although a small number of COVID‐19 patients have conjunctivitis, not all of them show positive test of SARS‐CoV‐2 nucleic acid in conjunctival sac swabs.
T15 1134-1371 Sentence denotes In addition, some patients did not have conjunctivitis despite positive test results for the SARS‐CoV‐2 nucleic acid in their conjunctiva sac swabs (Dr. Yanping Song from Wuhan City, China, the outbreak area in China, unpublished paper).
T16 1372-1614 Sentence denotes Interestingly, the medical history of the clinical physicians with COVID‐19 revealed that neither of them used eye goggles when examining (physician 1) and intubating infected patients (a high‐risk procedure to produce aerosol) (physician 2).
T17 1615-1907 Sentence denotes Studies show that, like the severe acute respiratory syndrome coronavirus (SARS‐CoV) that caused SARS, SARS‐CoV‐2 binds to human angiotensin‐enzyme II (ACE2), using it as a cell entry receptor to invade respiratory and lung epithelium through the spike (S) protein (Zhou et al., 2020a,2020b).
T18 1908-2100 Sentence denotes However, ACE2 is mainly expressed in posterior tissues of the eye, such as the retina and the retinal pigment epithelium, not in the human conjunctival and corneal epithelium (Choudhary et al.
T19 2101-2107 Sentence denotes 2017).
T20 2108-2196 Sentence denotes We presume that these previous studies ignored the characteristics of lacrimal drainage.
T21 2197-2249 Sentence denotes Tears are constantly renewed by the lacrimal system.
T22 2250-2406 Sentence denotes Therefore, we speculate that the virus enters the tears through droplets, which may pass through the nasolacrimal ducts and then into the respiratory tract.
T23 2407-2581 Sentence denotes Combined with all this information, we assert that, when coming into contact with confirmed or suspected cases of COVID‐19, healthcare workers should wear eye safety goggles.
T24 2582-2668 Sentence denotes This should become one of the critical measures for preventing the spread of COVID‐19.
T25 2669-2738 Sentence denotes The authors hope this topic is helpful for work in the outbreak area.