Id |
Subject |
Object |
Predicate |
Lexical cue |
T211 |
0-181 |
Sentence |
denotes |
The molecular mimicry between ATM and the saccharide part of GM1 gives new perspectives on the therapeutic effect of this macrolide antibiotic and this warrants further exploration. |
T212 |
182-374 |
Sentence |
denotes |
Moreover, the fact that ganglioside GM1 is a molecular target for CLQ-OH might explain the indication of this drug in rheumatological disorders, such as lupus and rheumatoid arthritis [35,36]. |
T213 |
375-467 |
Sentence |
denotes |
Indeed, GM1 overexpression and anti-GM1 antibodies are a hallmark of these diseases [37,38]. |
T214 |
468-618 |
Sentence |
denotes |
Thus, our data incidentally indicate that the therapeutic effect of CLQ-OH in these cases could also be related to its ganglioside-binding properties. |