PMC:7219429 / 16050-16795 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T115 0-144 Sentence denotes Fig. 3 Induced-fit conformational rearrangements during binding of ATM on the spike protein. (a) Docking of ATM on the spike protein (time = 0).
T116 145-236 Sentence denotes ATM is in yellow spheres, and the protein segment 134-137 is in balls and sticks rendition.
T117 237-295 Sentence denotes Three parts of the ATM molecule are marked with asterisks.
T118 296-450 Sentence denotes The orientation of the side chains of residues 134-137 is shown under the complex. (b) ATM bound to the spike protein after MD simulations (time = 50 ns).
T119 451-530 Sentence denotes Note that the complex has evolved according to a typical induced-fit mechanism.
T120 531-594 Sentence denotes The asterisks on ATM help visualize its conformational changes.
T121 595-745 Sentence denotes Reorientation of amino acid side chains is also clearly visible in the ATM-spike complex and in the isolated 134-137 fragment shown under the complex.