PMC:7219429 / 11098-12083 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T82 0-149 Sentence denotes Fig. 1 Structures of azithromycin (ATM) and SARS-CoV-2 spike protein trimer. (a) ATM, with both sugar-like pyranyl groups N-pyr and Ac-pyr indicated.
T83 150-374 Sentence denotes The molecules are shown in chemical, tube and sphere rendering (carbon in green, nitrogen in blue, oxygen in red, hydrogen in white). (b) Molecular structure similarity between ATM and the saccharide part of ganglioside GM1.
T84 375-514 Sentence denotes Both structures can adopt a globular shape the surface of which is covered with a patchwork of OH (arrows 1 and 2) and CH groups (arrow 3).
T85 515-794 Sentence denotes The volume occupied by ATM and the saccharide part of GM1 can be estimated to be 2082 and 2293 Å3, respectively. (c) front and above views of the trimeric spike, each spike protein subunit with a distinct surface colour (cyan for chain A, yellow for chain B, purple for chain C).
T86 795-917 Sentence denotes Atoms belonging to the ganglioside-binding domain of each subunit are visible underneath the slightly transparent surface.
T87 918-985 Sentence denotes The ganglioside-binding domains, the NTD and the RBD are indicated.