PMC:7212965 / 9650-12497 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T63 0-35 Sentence denotes Study Selection and Data Extraction
T64 36-184 Sentence denotes Independent screening of titles and abstracts was performed by independent reviewers (P.D., S.S., J.F.) to identify potential studies for inclusion.
T65 185-293 Sentence denotes A second reviewer (O.A.) subsequently reviewed the full-text articles and identified articles for inclusion.
T66 294-361 Sentence denotes Any disagreements about inclusion were resolved through discussion.
T67 362-487 Sentence denotes We incorporated any studies (prospective or retrospective) that reported on patient characteristics and symptoms of interest.
T68 488-605 Sentence denotes For studies published in Chinese, we used Google translate to assess for potential inclusion and for data extraction.
T69 606-843 Sentence denotes Due to concerns about inclusion of the same patients in different publications, we used a hierarchical model of data extraction to minimize double counting of patients across similar institutions with coinciding dates of study inclusion.
T70 844-1002 Sentence denotes We aimed to identify and include data from the largest possible cohort from each location or hospital.12 Data extraction was performed using a 2-step process.
T71 1003-1094 Sentence denotes The initial data extraction focused on data elements for study and patient characteristics.
T72 1095-1228 Sentence denotes Subsequently, we identified studies for full data extraction based on study location (unique hospitals) and total number of patients.
T73 1229-1463 Sentence denotes Additionally, when a study from a specific hospital did not provide all of the necessary information for the diarrhea symptoms, the next largest study from the same hospital (when available) was selected for inclusion in our analysis.
T74 1464-1552 Sentence denotes Data extraction was performed using a standardized Microsoft Excel data extraction form.
T75 1553-1766 Sentence denotes Data extraction was performed in pairs; one study author independently extracted data while a second reviewer checked for accuracy of the data extraction (S.S., O.A., S.M.S., P.D., J.D.F., J.K.L., Y.F.Y., H.B.E.).
T76 1767-1961 Sentence denotes Because the reporting of the data in the primary studies was suboptimal, a third reviewer (O.A.) additionally verified the extracted data to confirm the numbers and to resolve any disagreements.
T77 1962-2015 Sentence denotes Studies with discrepancies in the data were excluded.
T78 2016-2061 Sentence denotes The following data elements were extracted:1.
T79 2062-2180 Sentence denotes Study: author, year, location (hospital name, city, province or state), dates of inclusion, and date of last follow-up
T80 2181-2183 Sentence denotes 2.
T81 2184-2488 Sentence denotes Patient characteristics: number of patients, age (mean, median, interquartile interval or range), number of females, severity of illness, inclusion criteria (hospitalized or outpatients), GI comorbidities (pre-existing conditions, such as chronic liver disease, hepatitis, and inflammatory bowel disease)
T82 2489-2491 Sentence denotes 3.
T83 2492-2589 Sentence denotes Outcomes: diarrhea, nausea, vomiting, abdominal pain, and liver function test (LFT) abnormalities
T84 2590-2592 Sentence denotes 4.
T85 2593-2847 Sentence denotes Additional information: severity, characteristics, duration, timing (before or concurrent with respiratory symptoms), relationship with clinical outcomes (need for ventilator, survival, discharge, and continued hospitalization), and viral stool shedding.