PMC:7212949 / 50623-52178 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T512 0-8 Sentence denotes COVID-19
T513 9-316 Sentence denotes Study Wang et al (2020)N = 138, confirmed casesRetrospective study Cheng et al (2020)N = 701, confirmed casesRetrospective study Wang et al (2020)N = 205, confirmed casesClinicopathologic Li et al (2020)N = 193, confirmed casesRetrospective study Zhou et al (2020)N = 191, confirmed casesRetrospective study
T514 317-376 Sentence denotes Clinical Features • Coexisting chronic renal disease (2.9%)
T515 377-429 Sentence denotes • AKI (3.6%) • Coexisting chronic renal disease (2%)
T516 430-503 Sentence denotes • AKI (3.2%) N/A • AKI (28%) • AKI (15%) (Av 15 days after symptom onset)
T517 504-554 Sentence denotes Key findings on investigations ↑ Cr • ↑ Cr (14.4%)
T518 555-571 Sentence denotes • ↑ Urea (13.1%)
T519 572-589 Sentence denotes • eGFR<60 (13.1%)
T520 590-611 Sentence denotes • Proteinuria (43.9%)
T521 612-685 Sentence denotes • Hematuria (26.7%) No viral detection in urine (72 samples) • ↑ Cr (10%)
T522 686-701 Sentence denotes • ↑ Urea (14.%)
T523 702-721 Sentence denotes • Proteinuria (59%)
T524 722-744 Sentence denotes • Hematuria (44%) ↑ Cr
T525 745-841 Sentence denotes Key study findings and message • ICU patients more likely to have ↑ Cr (P = 0.04), ↑ BUN (0.001)
T526 842-1002 Sentence denotes • Cr and urea increased with disease progression • ↑ Cr at admission more common in males, older patients, more severe disease (P < 0.001, P < 0.001, P = 0.026)
T527 1003-1128 Sentence denotes • AKI, in hospital death, mechanical ventilation more common in patients with baseline ↑ Cr (P < 0.001, P < 0.001, P = 0.012)
T528 1129-1266 Sentence denotes • Higher in hospital death rate with proteinuria, hematuria, baseline ↑ Cr, Urea, AKI Stage 2 or 3 (P < 0.001; P = 0.003 for AKI stage 1)
T529 1267-1374 Sentence denotes • Renal features may be due to direct viral effect, immune mediated, virus induced cytokines and mediators.
T530 1375-1489 Sentence denotes No viral shedding in urine AKI associated with severe outcome (P < 0.001) • ↑ Cr associated with in-hospital death
T531 1490-1501 Sentence denotes (P = 0.045)
T532 1502-1555 Sentence denotes • Higher incidence of AKI in nonsurvivors (P < 0.001)