Id |
Subject |
Object |
Predicate |
Lexical cue |
T512 |
0-8 |
Sentence |
denotes |
COVID-19 |
T513 |
9-316 |
Sentence |
denotes |
Study Wang et al (2020)N = 138, confirmed casesRetrospective study Cheng et al (2020)N = 701, confirmed casesRetrospective study Wang et al (2020)N = 205, confirmed casesClinicopathologic Li et al (2020)N = 193, confirmed casesRetrospective study Zhou et al (2020)N = 191, confirmed casesRetrospective study |
T514 |
317-376 |
Sentence |
denotes |
Clinical Features • Coexisting chronic renal disease (2.9%) |
T515 |
377-429 |
Sentence |
denotes |
• AKI (3.6%) • Coexisting chronic renal disease (2%) |
T516 |
430-503 |
Sentence |
denotes |
• AKI (3.2%) N/A • AKI (28%) • AKI (15%) (Av 15 days after symptom onset) |
T517 |
504-554 |
Sentence |
denotes |
Key findings on investigations ↑ Cr • ↑ Cr (14.4%) |
T518 |
555-571 |
Sentence |
denotes |
• ↑ Urea (13.1%) |
T519 |
572-589 |
Sentence |
denotes |
• eGFR<60 (13.1%) |
T520 |
590-611 |
Sentence |
denotes |
• Proteinuria (43.9%) |
T521 |
612-685 |
Sentence |
denotes |
• Hematuria (26.7%) No viral detection in urine (72 samples) • ↑ Cr (10%) |
T522 |
686-701 |
Sentence |
denotes |
• ↑ Urea (14.%) |
T523 |
702-721 |
Sentence |
denotes |
• Proteinuria (59%) |
T524 |
722-744 |
Sentence |
denotes |
• Hematuria (44%) ↑ Cr |
T525 |
745-841 |
Sentence |
denotes |
Key study findings and message • ICU patients more likely to have ↑ Cr (P = 0.04), ↑ BUN (0.001) |
T526 |
842-1002 |
Sentence |
denotes |
• Cr and urea increased with disease progression • ↑ Cr at admission more common in males, older patients, more severe disease (P < 0.001, P < 0.001, P = 0.026) |
T527 |
1003-1128 |
Sentence |
denotes |
• AKI, in hospital death, mechanical ventilation more common in patients with baseline ↑ Cr (P < 0.001, P < 0.001, P = 0.012) |
T528 |
1129-1266 |
Sentence |
denotes |
• Higher in hospital death rate with proteinuria, hematuria, baseline ↑ Cr, Urea, AKI Stage 2 or 3 (P < 0.001; P = 0.003 for AKI stage 1) |
T529 |
1267-1374 |
Sentence |
denotes |
• Renal features may be due to direct viral effect, immune mediated, virus induced cytokines and mediators. |
T530 |
1375-1489 |
Sentence |
denotes |
No viral shedding in urine AKI associated with severe outcome (P < 0.001) • ↑ Cr associated with in-hospital death |
T531 |
1490-1501 |
Sentence |
denotes |
(P = 0.045) |
T532 |
1502-1555 |
Sentence |
denotes |
• Higher incidence of AKI in nonsurvivors (P < 0.001) |