PMC:7212949 / 22124-24029 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T225 0-56 Sentence denotes SARS (only studies with large study population included)
T226 57-375 Sentence denotes Study Booth et al (2003)N = 144, confirmed casesRetrospective study Li et al (2003)N = 46, confirmed casesProspective study Pan et al (2003)N = 15, confirmed casesRetrospective study Ding et al (2004)N = 8 (4 confirmed cases, 4 control)Clinicopathologic study Yu et al (2006)N = 121, confirmed casesRetrospective study
T227 376-612 Sentence denotes Clinical features • Chest pain (10%)• ↑HR (46%) • No chest pain or overt CHF on admission• ↓HR (non-ICU) ↑HR (ICU)•CHF exacerbation • Sudden cardiac arrest (100%)• MI and arrhythmia (33%) • Chest pain • ↑HR (71.9%) (62.8%, 45.4%, 35.5%)
T228 613-707 Sentence denotes • ↓BP (50.4%) (28.1%, 21.5%, 14.8% during the first, second, third week)↓HR, transient (14.9%)
T229 708-768 Sentence denotes • Reversible cardiomegaly (10.7%), no clinical heart failure
T230 769-792 Sentence denotes • Chest discomfort (7%)
T231 793-812 Sentence denotes • Palpitations (4%)
T232 813-857 Sentence denotes Key findings on investigations • ↓Ca++ (60%)
T233 858-869 Sentence denotes • ↓K+ (26%)
T234 870-883 Sentence denotes • ↓Mg++ (18%)
T235 884-895 Sentence denotes • ↓P+ (27%)
T236 896-916 Sentence denotes • ↑ LDH (87%) • ↑ CK
T237 917-924 Sentence denotes • ↑ LDH
T238 925-930 Sentence denotes • ↓Hb
T239 931-942 Sentence denotes • EKG: RBBB
T240 943-1000 Sentence denotes • Echo: ↓LVEF • Abnormal cardiac enzymes (66%) N/A • ↑ CK
T241 1001-1032 Sentence denotes • ↑CK (26%) without TnI or CKMB
T242 1033-1040 Sentence denotes • ↑ LDH
T243 1041-1065 Sentence denotes • CXR or CT abnormality:
T244 1066-1070 Sentence denotes 100%
T245 1071-1124 Sentence denotes Histopathology N/A N/A N/A • Myocardial stromal edema
T246 1125-1165 Sentence denotes • Infiltration of vessels by lymphocytes
T247 1166-1194 Sentence denotes • Focal hyaline degeneration
T248 1195-1219 Sentence denotes • Muscle fiber lysis N/A
T249 1220-1270 Sentence denotes Key study findings and message • 20% ICU admission
T250 1271-1306 Sentence denotes • 6.5% Case fatality rate (21 days)
T251 1307-1525 Sentence denotes • Diabetes and other comorbidities independently associated with poor prognosis Possibly reversible subclinical diastolic impairment seen in SARS patients Proposed causes of SCD:• Hypoxemia leading to myocardial strain
T252 1526-1558 Sentence denotes • Direct viral myocardial injury
T253 1559-1599 Sentence denotes • Stress aggravates pre-existing disease
T254 1600-1767 Sentence denotes • Sympathetic response causing electrical myocardial instability ACE2 expressed in heart, but virus not detected • ↑CK likely due to myositis as cardiac enzymes normal
T255 1768-1787 Sentence denotes • 15% ICU admission
T256 1788-1832 Sentence denotes • 18 (5) days mean duration of hospital stay
T257 1833-1872 Sentence denotes • Tachycardia persists during follow up
T258 1873-1905 Sentence denotes • Cardiac arrhythmia is uncommon