Id |
Subject |
Object |
Predicate |
Lexical cue |
T225 |
0-56 |
Sentence |
denotes |
SARS (only studies with large study population included) |
T226 |
57-375 |
Sentence |
denotes |
Study Booth et al (2003)N = 144, confirmed casesRetrospective study Li et al (2003)N = 46, confirmed casesProspective study Pan et al (2003)N = 15, confirmed casesRetrospective study Ding et al (2004)N = 8 (4 confirmed cases, 4 control)Clinicopathologic study Yu et al (2006)N = 121, confirmed casesRetrospective study |
T227 |
376-612 |
Sentence |
denotes |
Clinical features • Chest pain (10%)• ↑HR (46%) • No chest pain or overt CHF on admission• ↓HR (non-ICU) ↑HR (ICU)•CHF exacerbation • Sudden cardiac arrest (100%)• MI and arrhythmia (33%) • Chest pain • ↑HR (71.9%) (62.8%, 45.4%, 35.5%) |
T228 |
613-707 |
Sentence |
denotes |
• ↓BP (50.4%) (28.1%, 21.5%, 14.8% during the first, second, third week)↓HR, transient (14.9%) |
T229 |
708-768 |
Sentence |
denotes |
• Reversible cardiomegaly (10.7%), no clinical heart failure |
T230 |
769-792 |
Sentence |
denotes |
• Chest discomfort (7%) |
T231 |
793-812 |
Sentence |
denotes |
• Palpitations (4%) |
T232 |
813-857 |
Sentence |
denotes |
Key findings on investigations • ↓Ca++ (60%) |
T233 |
858-869 |
Sentence |
denotes |
• ↓K+ (26%) |
T234 |
870-883 |
Sentence |
denotes |
• ↓Mg++ (18%) |
T235 |
884-895 |
Sentence |
denotes |
• ↓P+ (27%) |
T236 |
896-916 |
Sentence |
denotes |
• ↑ LDH (87%) • ↑ CK |
T237 |
917-924 |
Sentence |
denotes |
• ↑ LDH |
T238 |
925-930 |
Sentence |
denotes |
• ↓Hb |
T239 |
931-942 |
Sentence |
denotes |
• EKG: RBBB |
T240 |
943-1000 |
Sentence |
denotes |
• Echo: ↓LVEF • Abnormal cardiac enzymes (66%) N/A • ↑ CK |
T241 |
1001-1032 |
Sentence |
denotes |
• ↑CK (26%) without TnI or CKMB |
T242 |
1033-1040 |
Sentence |
denotes |
• ↑ LDH |
T243 |
1041-1065 |
Sentence |
denotes |
• CXR or CT abnormality: |
T244 |
1066-1070 |
Sentence |
denotes |
100% |
T245 |
1071-1124 |
Sentence |
denotes |
Histopathology N/A N/A N/A • Myocardial stromal edema |
T246 |
1125-1165 |
Sentence |
denotes |
• Infiltration of vessels by lymphocytes |
T247 |
1166-1194 |
Sentence |
denotes |
• Focal hyaline degeneration |
T248 |
1195-1219 |
Sentence |
denotes |
• Muscle fiber lysis N/A |
T249 |
1220-1270 |
Sentence |
denotes |
Key study findings and message • 20% ICU admission |
T250 |
1271-1306 |
Sentence |
denotes |
• 6.5% Case fatality rate (21 days) |
T251 |
1307-1525 |
Sentence |
denotes |
• Diabetes and other comorbidities independently associated with poor prognosis Possibly reversible subclinical diastolic impairment seen in SARS patients Proposed causes of SCD:• Hypoxemia leading to myocardial strain |
T252 |
1526-1558 |
Sentence |
denotes |
• Direct viral myocardial injury |
T253 |
1559-1599 |
Sentence |
denotes |
• Stress aggravates pre-existing disease |
T254 |
1600-1767 |
Sentence |
denotes |
• Sympathetic response causing electrical myocardial instability ACE2 expressed in heart, but virus not detected • ↑CK likely due to myositis as cardiac enzymes normal |
T255 |
1768-1787 |
Sentence |
denotes |
• 15% ICU admission |
T256 |
1788-1832 |
Sentence |
denotes |
• 18 (5) days mean duration of hospital stay |
T257 |
1833-1872 |
Sentence |
denotes |
• Tachycardia persists during follow up |
T258 |
1873-1905 |
Sentence |
denotes |
• Cardiac arrhythmia is uncommon |