PMC:7200337 / 47642-48873 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T262 0-95 Sentence denotes There is great interest in understanding the lifespan of B cell memory responses to SARS-CoV-2.
T263 96-249 Sentence denotes Protection from reinfection has direct medical and social consequences as the world works to develop vaccination strategies and resume normal activities.
T264 250-491 Sentence denotes In COVID-19 patients, evidence of near-universal seroconversion and the lack of substantial descriptions of reinfection point to a robust antibody response, which, along with the T cell memory response, would offer protection to reinfection.
T265 492-850 Sentence denotes Indeed, a case study of a single patient described induction of CD38HiCD27Hi antibody-secreting cells (ASCs), concomitant with an increase in circulating follicular T helper cells (Tfh) cells (Thevarajan et al., 2020), and a scRNA-seq study of PBMCs from critically ill and recently recovered individuals revealed a plasma cell population (Guo et al., 2020).
T266 851-974 Sentence denotes In addition, IgG memory cells specific to the RBD have been identified in the blood of COVID-19 patients (Ju et al., 2020).
T267 975-1231 Sentence denotes Consistent with the development of immunity after COVID-19 infection, a recent study of SARS-CoV-2 infection in rhesus macaques found that two macaques that had resolved the primary infection were resistant to reinfection 28 days later (Bao et al., 2020b).