Id |
Subject |
Object |
Predicate |
Lexical cue |
T2 |
0-36 |
Sentence |
denotes |
SARS-CoV-2 spike protein, elaborated |
T3 |
37-188 |
Sentence |
denotes |
Vaccine development for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is focused on the trimeric spike protein that initiates infection. |
T4 |
189-252 |
Sentence |
denotes |
Each protomer in the trimeric spike has 22 glycosylation sites. |
T5 |
253-390 |
Sentence |
denotes |
How these sites are glycosylated may affect which cells the virus can infect and could shield some epitopes from antibody neutralization. |
T6 |
391-610 |
Sentence |
denotes |
Watanabe et al. expressed and purified recombinant glycosylated spike trimers, proteolysed them to yield glycopeptides containing a single glycan, and determined the composition of the glycan sites by mass spectrometry. |
T7 |
611-734 |
Sentence |
denotes |
The analysis provides a benchmark that can be used to measure antigen quality as vaccines and antibody tests are developed. |
T8 |
735-756 |
Sentence |
denotes |
Science this issue p. |
T9 |
757-760 |
Sentence |
denotes |
330 |