PMC:7195088 / 67202-68210 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T473 0-104 Sentence denotes The optimal time of chloroquine/hydroxychloroquine and corticosteroids initiation still remains unknown.
T474 105-601 Sentence denotes Although based on low-level evidence, the positive effect of virus clearance observed by Gautret et al. [41] was observed in a mixed group of non-ICU patients with upper respiratory tract symptoms, non-ICU patients with lower respiratory tract symptoms and asymptomatic subjects, which overall may support a positive effect of early hydroxychloroquine initiation in non-ICU settings (although information on the exact time of treatment initiation with respect to symptoms onset was not provided).
T475 602-749 Sentence denotes With regard to steroid treatment, there is currently no evidence of a positive impact of early initiation in non–critically ill, non-ARDS patients.
T476 750-1008 Sentence denotes Although lack of evidence is not a synonym of lack of effect, in our opinion, steroid treatment, considering also its potential detrimental effects, should currently be limited to ARDS patients or non-ARDS patients with worsening conditions (see question 5).