LitCovid-sentences  

PMC:7195088 / 42615-44426 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T313 0-19 Sentence denotes Drug Adverse events
T314 20-105 Sentence denotes Lopinavir/ritonavir • Hypercholesterolaemia and increased serum triglycerides (3–39%)
T315 106-149 Sentence denotes • Increased γ-glutamyl transferase (10–29%)
T316 150-201 Sentence denotes • Diarrhoea (7–28%; greater with once-daily dosing)
T317 202-235 Sentence denotes • Increased serum ALT (grade 3/4:
T318 236-242 Sentence denotes 1–11%)
T319 243-259 Sentence denotes • Nausea (5–16%)
T320 260-301 Sentence denotes • Upper respiratory tract infection (14%)
T321 302-326 Sentence denotes • Abdominal pain (1–11%)
T322 327-344 Sentence denotes • Vomiting (2–7%)
T323 345-359 Sentence denotes • Fatigue (8%)
T324 360-406 Sentence denotes • Increased serum amylase and/or lipase (3–8%)
T325 407-424 Sentence denotes • Headache (2–6%)
T326 425-442 Sentence denotes • Skin rash (≤5%)
T327 443-468 Sentence denotes • Neutropenia (grade 3/4:
T328 469-474 Sentence denotes 1–5%)
T329 475-489 Sentence denotes • Anxiety (4%)
T330 490-506 Sentence denotes • Insomnia (≤4%)
T331 507-577 Sentence denotes Chloroquine/hydroxychloroquine • Retinopathy (4% of treated patients)a
T332 578-829 Sentence denotes • Other adverse effects with unknown frequency included Stevens-Johnson syndrome, abdominal pain, diarrhoea, nausea, vomiting, agranulocytosis, leukopenia, thrombocytopenia, abnormal hepatic function tests, acute hepatic ailure, myopathy, bronchospasm
T333 830-936 Sentence denotes • Risk of prolonged QT interval, further increased when administered with fluoroquinolones or azithromycin
T334 937-992 Sentence denotes Tocilizumab • Increased serum ALT (≤36%) and AST (≤22%)
T335 993-1028 Sentence denotes • Increased LDL cholesterol (9–10%)
T336 1029-1062 Sentence denotes • Injection site reaction (4–10%)
T337 1063-1086 Sentence denotes • Neutropenia (grade 3:
T338 1087-1114 Sentence denotes 2–7% of all adult patients)
T339 1115-1132 Sentence denotes • Headache (1–7%)
T340 1133-1154 Sentence denotes • Hypertension (1–6%)
T341 1155-1171 Sentence denotes • Dizziness (3%)
T342 1172-1194 Sentence denotes • Hypothyroidism (<2%)
T343 1195-1216 Sentence denotes • Abdominal pain (2%)
T344 1217-1253 Sentence denotes • Oral mucosa or gastric ulcers (2%)
T345 1254-1427 Sentence denotes • Infections due to Pneumocystis, Mycobacterium tuberculosis and varicella zoster have been reported after tocilizumab, but their prevalence has not been clearly established
T346 1428-1472 Sentence denotes Anakinra • Injection site reactionb (24–71%)
T347 1473-1586 Sentence denotes • Antibody development (up to 50% of the patients but no correlation of antibody development and adverse effects)
T348 1587-1619 Sentence denotes • Headache and vomiting (12–14%)
T349 1620-1641 Sentence denotes • Arthralgia (10–12%)
T350 1642-1658 Sentence denotes • Fever (10–12%)
T351 1659-1753 Sentence denotes • Haematologic disorder including eosinophilia, leukopenia and change in platelet count (2–9%)
T352 1754-1783 Sentence denotes • Nausea and diarrhoea (7–8%)
T353 1784-1811 Sentence denotes • Serious infectionc (2–3%)