PMC:7195088 / 33621-34332 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T270 0-37 Sentence denotes Anakinra Antagonist of IL-1 receptor.
T271 38-294 Sentence denotes IL-1 is one of the main drivers of immunologic response and symptoms in patients with cytokine-release syndrome. • Not available • Comparison of anakinra vs. emapalumab (anti–interferon γ monoclonal antibody) vs. standard of care in patients with COVID-19.
T272 295-344 Sentence denotes Open-label RCT (NCT04324021, not yet recruiting).
T273 345-391 Sentence denotes Primary endpoint: treatment success at day 15.
T274 392-593 Sentence denotes • Comparison of tocilizumab vs. anakinra (recombinant IL-1 receptor antagonist) vs. siltuximab vs. anakinra plus siltuximab vs. anakinra plus tocilizumab vs. standard of care in patients with COVID-19.
T275 594-643 Sentence denotes Open-label RCT (NCT04330638, not yet recruiting).
T276 644-711 Sentence denotes Primary endpoint: time to clinical improvement (follow-up 15 days).