PMC:7189872 / 99-1303 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE-old TextAE

Id Subject Object Predicate Lexical cue
T3 0-112 Sentence denotes A new virus termed SARS-COV-2 (causing COVID-19 disease) can exhibit a progressive, fatal impact on individuals.
T4 113-210 Sentence denotes The World Health Organization (WHO) has declared the spread of the virus to be a global pandemic.
T5 211-304 Sentence denotes Currently, there are over 1 million cases and over 100,000 confirmed deaths due to the virus.
T6 305-372 Sentence denotes Hence, prophylactic and therapeutic strategies are promptly needed.
T7 373-471 Sentence denotes In this study we report an epitope, ITLCFTLKR, which is biochemically fit to HLA allelic proteins.
T8 472-559 Sentence denotes We propose that this could be used as a potential vaccine candidate against SARS-COV-2.
T9 560-694 Sentence denotes A selected putative epitope and HLA-allelic complexes show not only better binding scores, but also RMSD values in the range of 0–1 Å.
T10 695-792 Sentence denotes This epitope was found to have a 99.8% structural favorability as per Ramachandran-plot analysis.
T11 793-932 Sentence denotes Similarly, a suitable range of IC50 values and population coverage was obtained to represent greater validation of T-cell epitope analysis.
T12 933-1061 Sentence denotes Stability analysis using MDWeb and half-life analysis using the ProtParam tool has confirmed that this epitope is well-selected.
T13 1062-1204 Sentence denotes This new methodology of epitope-based vaccine prediction is fundamental and fast in application, ad can be economically beneficial and viable.