Id |
Subject |
Object |
Predicate |
Lexical cue |
T74 |
0-51 |
Sentence |
denotes |
3.1 T-cell epitopes prediction and VaxiJen scoring |
T75 |
52-337 |
Sentence |
denotes |
Non-allergen proteins selected (Table 1) based on allergenicity scores (by deploying AllergenFP 1.0) New to NetMHCII PAN 3.2 and NETMHC 4.0 servers for determining 1-log50k value and affinity values for selecting the best possible pair of epitopes with their corresponding HLA alleles. |
T76 |
338-527 |
Sentence |
denotes |
In Table 2 and Table 3 , results for MHC Class I HLA and MHC Class II HLA alleles paired epitopes along with their VaxiJen scores were represented respectively, to obtain putative epitopes. |
T77 |
528-572 |
Sentence |
denotes |
The results are self-explanatory in Fig. 2 . |
T78 |
573-734 |
Sentence |
denotes |
Graphical representation of selected peptides for docking are based on their interaction with MHC Class I and Class II HLA alleles along with their antigenicity. |
T79 |
735-959 |
Sentence |
denotes |
Table 2 Probable antigenic epitopes and MHC I Allele interaction based on NETMHC 4.0 server and VaxiJen 2.0 scores (≥1.0) for antigenicity prediction. (* - sign is used for no interaction any HLA Allele under consideration). |
T80 |
960-1054 |
Sentence |
denotes |
NCBI-GenBank ID MHC I Allele POS Core peptide 1-LOG50K Affinity(nM) Vaxijen score Antigenicity |
T81 |
1055-1114 |
Sentence |
denotes |
QHD43417.1 HLA-A*68:01 7 FTIGTVTLK 0.853 4.9 2.0317 ANTIGEN |
T82 |
1115-1166 |
Sentence |
denotes |
HLA-A*31:01 125 RLWLCWKCR 0.74 16.59 1.1604 ANTIGEN |
T83 |
1167-1204 |
Sentence |
denotes |
QHD43418.1 – – – – – – NO INTERACTION |
T84 |
1205-1266 |
Sentence |
denotes |
QHD43419.1 HLA-A*11:01 5 GTITVEELK 0.719 20.98 1.0976 ANTIGEN |
T85 |
1267-1329 |
Sentence |
denotes |
QHD43421.1 HLA-A*11:01 109 ITLCFTLKR 0.71 22.97 2.0208 ANTIGEN |
T86 |
1330-1382 |
Sentence |
denotes |
HLA-A*68:01 109 ITLCFTLKR 0.695 27.24 2.0208 ANTIGEN |
T87 |
1383-1435 |
Sentence |
denotes |
HLA-A*23:01 107 VFITLCFTL 0.621 60.42 1.2490 ANTIGEN |
T88 |
1436-1473 |
Sentence |
denotes |
QHD43423.2 – – – – – – NO INTERACTION |
T89 |
1474-1707 |
Sentence |
denotes |
Table 3 Probable antigenic epitopes and MHC II Allele interaction based on NETMHC II PRED 3.2 server and VaxiJen 2.0 scores (≥1.0) for antigenicity prediction. (* - sign is used for no interaction any HLA Allele under consideration). |
T90 |
1708-1804 |
Sentence |
denotes |
NCBI-GenBank ID MHC II Allele POS Core peptide 1- LOG50K Affinity(nM) Vaxijen score Antigenicity |
T91 |
1805-1842 |
Sentence |
denotes |
QHD43417.1 – – – – – – NO INTERACTION |
T92 |
1843-1880 |
Sentence |
denotes |
QHD43418.1 – – – – – – NO INTERACTION |
T93 |
1881-1947 |
Sentence |
denotes |
QHD43419.1 HLA-DRB1*04:01 55 WLLWPVTA 0.282 2375.78 1.0631 ANTIGEN |
T94 |
1948-2014 |
Sentence |
denotes |
QHD43421.1 HLA-DRB1*01:01 74 VYQLRARSV 0.484 267.05 1.3108 ANTIGEN |
T95 |
2015-2071 |
Sentence |
denotes |
HLA-DRB1*07:01 74 VYQLRARSV 0.342 1235.08 1.3108 ANTIGEN |
T96 |
2072-2109 |
Sentence |
denotes |
QHD43423.2 – – – – – – NO INTERACTION |
T97 |
2110-2274 |
Sentence |
denotes |
Fig. 2 Graphical representation of selected peptides for docking based on their interaction with MHC Class I and Class II HLA alleles along with their Antigenicity. |