LitCovid-sentences  

PMC:7180007 / 14264-15852 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T95 0-25 Sentence denotes Pharmacological therapies
T96 26-166 Sentence denotes Pharmacological treatment of depression, anxiety, and related disorders is an alternate or in some cases adjunct to psychological treatment.
T97 167-302 Sentence denotes Drugs that influence glutamatergic, adrenergic, serotonergic, endocannabinoid systems and various neuropeptide are generally preferred.
T98 303-502 Sentence denotes In such therapies antidepressants are the first-line pharmacological treatment options such as serotonin-noradrenaline reuptake inhibitors (SNRIs) and selective serotonin reuptake inhibitors (SSRIs).
T99 503-617 Sentence denotes These drugs are effective against several types of mental disorders specifically depression and anxiety (S28-S30).
T100 618-797 Sentence denotes Agomelatine (a melatonin receptor agonist) and Vilazodone (a serotonin reuptake inhibitor and partial agonist of serotonin receptors) are also recommended in depression (S27,S31).
T101 798-910 Sentence denotes Among second-line agents for anxiety and depressive disorders benzodiazepines have been found with good results.
T102 911-1020 Sentence denotes However, they have some serious adverse effects including dizziness, drowsiness, and increased risk of falls.
T103 1021-1138 Sentence denotes In such cases the alternative drugs (that modulate GABA signaling), including, gabapentin and pregabalin can be used.
T104 1139-1280 Sentence denotes In case of severe anxiety, risperidone or quetiapine (atypical antipsychotics) should be given as an adjunct to SSRIs or SNRIs (S27,S31-S33).
T105 1281-1409 Sentence denotes All these drugs could be effective; however, their use should be only recommended when psychological approaches are not working.
T106 1410-1588 Sentence denotes Nevertheless, the use of both pharmacotherapy and psychotherapy (combined therapy) is more beneficial and effective in the case of chronic anxiety and depressive disorders (S27).