Id |
Subject |
Object |
Predicate |
Lexical cue |
T47 |
0-57 |
Sentence |
denotes |
The Role of Diagnostic Testing in the SARS–CoV-2 Pandemic |
T48 |
58-247 |
Sentence |
denotes |
The primary goal of epidemic containment is to reduce disease transmission by reducing the number of susceptible persons in the population or by reducing the basic reproductive number (R0). |
T49 |
248-429 |
Sentence |
denotes |
This number is modulated by such factors as the duration of viral shedding, the infectiousness of the organism, and the contact matrix between infected and susceptible persons (18). |
T50 |
430-610 |
Sentence |
denotes |
Given the lack of effective vaccines or treatments (19), the only currently available lever to reduce SARS–CoV-2 transmission is to identify and isolate persons who are contagious. |
T51 |
611-679 |
Sentence |
denotes |
Deployment of SARS–CoV-2 testing has varied widely across the globe. |
T52 |
680-801 |
Sentence |
denotes |
A few Asian countries have illustrated the power of preparedness, flexible isolation systems, and intensive case finding. |
T53 |
802-900 |
Sentence |
denotes |
South Korea dramatically slowed the epidemic by implementing an unprecedented testing effort (20). |
T54 |
901-1069 |
Sentence |
denotes |
Using innovative measures, South Korea performed more than 300 000 tests (5828.6 tests per million persons) in the 9 weeks after the first case was identified (20, 21). |
T55 |
1070-1157 |
Sentence |
denotes |
Singapore used a broad case definition, aggressive contact tracing, and isolation (10). |
T56 |
1158-1432 |
Sentence |
denotes |
Moreover, to identify infected persons not meeting the case definition, Singapore screened patients with pneumonia and influenza-like illnesses in hospitals and primary care settings, severely ill patients in intensive care, and deaths with a possible infectious cause (10). |
T57 |
1433-1483 |
Sentence |
denotes |
Taiwan and Hong Kong used similar approaches (22). |
T58 |
1484-1632 |
Sentence |
denotes |
These countries rapidly deployed resource-intensive strategies that prioritized aggressive testing and isolation to interrupt transmission (20, 22). |
T59 |
1633-1815 |
Sentence |
denotes |
In the face of widespread transmission, the role of diagnostic testing is contingent on the type of testing available, the resources required for testing, and time to obtain results. |
T60 |
1816-2039 |
Sentence |
denotes |
For example, rapidly identifying cases among hospitalized patients remains a high priority to properly allocate personal protective equipment and to prevent nosocomial spread with subsequent community transmission (23, 24). |
T61 |
2040-2146 |
Sentence |
denotes |
Likewise, specific treatment decisions and enrollment in ongoing clinical trials require prompt diagnosis. |