| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T135 |
0-8 |
Sentence |
denotes |
Serology |
| T136 |
9-303 |
Sentence |
denotes |
Serologic tests that identify antibodies (such as IgA, IgM, and IgG) to SARS–CoV-2 from clinical specimens (such as blood or saliva), such as enzyme-linked immunosorbent assays, may be less complex than molecular tests and have the potential to be used for diagnosis in certain situations (46). |
| T137 |
304-479 |
Sentence |
denotes |
However, their utility for diagnosing acute infections is probably limited around the time of symptom onset, when viral shedding and transmission risk seem to be highest (32). |
| T138 |
480-562 |
Sentence |
denotes |
Antibody responses to infection take days to weeks to be reliably detectable (46). |
| T139 |
563-679 |
Sentence |
denotes |
Negative results would not exclude SARS–CoV-2 infection, particularly among those with recent exposure to the virus. |
| T140 |
680-885 |
Sentence |
denotes |
Cross-reactivity of antibody to non–SARS–CoV-2 coronavirus proteins is also a potential problem, whereby positive results may be the result of past or present infection with other human coronaviruses (47). |
| T141 |
886-1098 |
Sentence |
denotes |
Serologic assays might be more relevant in scenarios in which patients present to medical care with late complications of disease, when RT-PCR may be falsely negative, because viral shedding drops over time (48). |
| T142 |
1099-1344 |
Sentence |
denotes |
The development of serologic assays that accurately assess prior infection and immunity to SARS–CoV-2 will be essential for epidemiologic studies, ongoing surveillance, vaccine studies, and potentially for risk assessment of health care workers. |
| T143 |
1345-1466 |
Sentence |
denotes |
Immunoassays are already on the market in some countries, but their diagnostic accuracy and optimal use remain undefined. |
