LitCovid-sentences  

PMC:7166305 / 141-1580 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T4 0-10 Sentence denotes Background
T5 11-107 Sentence denotes The pandemic of coronavirus disease 2019 (COVID-19) has become a global threat to public health.
T6 108-157 Sentence denotes The lipid pathophysiology in COVID-19 is unknown.
T7 159-166 Sentence denotes Methods
T8 167-362 Sentence denotes In this retrospective longitudinal study, we monitored the serum lipids in 17 surviving and 4 non-surviving COVID-19 cases prior to their viral infections and duration the entire disease courses.
T9 364-371 Sentence denotes Results
T10 372-660 Sentence denotes In surviving cases, the low-density lipoprotein (LDL) levels decreased significantly on admission as compared with the levels before infection; the LDL levels remained constantly low during the disease progression and resumed to the original levels when patients recovered (pre-infection:
T11 661-689 Sentence denotes 3.5 (3.0–4.4); on admission:
T12 690-727 Sentence denotes 2.8 (2.3–3.1), p < 0.01; progression:
T13 728-753 Sentence denotes 2.5 (2.3–3.0); discharge:
T14 754-794 Sentence denotes 3.6 (2.7–4.1); median (IQR), in mmol/L).
T15 795-949 Sentence denotes In non-surviving patients, LDL levels showed an irreversible and continuous decrease until death (1.1 (0.9–1.2), p = 0.02 versus the levels on admission).
T16 950-1068 Sentence denotes The ratio changes of LDL levels inversely correlated with ratio changes of high-sensitivity C-reactive protein levels.
T17 1069-1191 Sentence denotes Logistic regression analysis showed increasing odds of lowered LDL levels associated with disease progression (odds ratio:
T18 1192-1205 Sentence denotes 4.48, 95% IC:
T19 1206-1263 Sentence denotes 1.55–12.92, p = 0.006) and in-hospital death (odds ratio:
T20 1264-1278 Sentence denotes 21.72, 95% IC:
T21 1279-1303 Sentence denotes 1.40–337.54, p = 0.028).
T22 1305-1316 Sentence denotes Conclusions
T23 1317-1439 Sentence denotes LDL levels inversely correlated to disease severities, which could be a predictor for disease progress and poor prognosis.