PMC:7164862 / 63-842 JSON TXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id	Subject	Object	Predicate	Lexical cue
T2	0-275	Sentence	denotes	In-vitro studies have shown that chloroquine is effective against several viruses, including severe acute respiratory syndrome coronavirus (SARS-CoV).1 Multiple mechanisms of action have been identified for chloroquine that disrupt the early stage of coronavirus replication.
T3	276-779	Sentence	denotes	Moreover, chloroquine affects immune system activity by mediating an anti-inflammatory response, which might reduce damage due to the exaggerated inflammatory response.1 At the time of the SARS epidemic, chloroquine was suggested as a drug that could be used to treat this infection.2 However, randomised, double-blind, controlled studies in humans to evaluate its efficacy for this use were not done, and the true clinical efficacy of chloroquine in treating coronavirus infections was not established.