PMC:7163185 / 4621-6266 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T62 0-472 Sentence denotes Recently, a number of studies have described the epidemiological and clinical characters of COVID-19.2, 3, 4 A study of 41 patients with COVID-19 has suggested that 12% of the mild and severe cases combined showed increased hyper sensitivity troponin I, suggesting acute myocardial injury.2 It is also reported that severe acute respiratory syndrome coronavirus (SARS-CoV)6 and Middle East respiratory syndrome coronavirus (MERS-CoV)7 have caused critical cardiac lesions.
T63 473-589 Sentence denotes In the present study, we have focused on cardiac lesion biomarkers in severe and very severe patients with COVID-19.
T64 590-660 Sentence denotes We have proved elevation of cTnI, CK, HBDB, and LDH in critical cases.
T65 661-791 Sentence denotes It is important to notify that, in very severe group, 8/8 patients exhibit cTnI above reference level; while 1/26 in severe group.
T66 792-884 Sentence denotes This suggests that elevated cTnI could be a potential indicator for critically ill patients.
T67 885-1173 Sentence denotes It is worth notifying that among the 8 critically ill patients enrolled, the kidney and liver function markers are not as significantly disturbed as the cardiac lesion markers, suggesting that most patients enrolled have not been suffering from multiple organ dysfunction syndrome (MODS).
T68 1174-1349 Sentence denotes Thus, the consistently high cTnI levels in very severe group point to the importance that the heart injury could be a distinct, or even lethal feature in very severe COVID-19.
T69 1350-1467 Sentence denotes Protecting from myocardial injury could be of vital importance in clinical treatment for reducing the mortality rate.
T70 1468-1511 Sentence denotes The study was limited by small sample size.
T71 1512-1591 Sentence denotes And we haven't analyzed the echocardiography and MRI for the patients enrolled.
T72 1592-1645 Sentence denotes Further analysis is needed to determine the etiology.